Primary thyroid mucosa-associated lymphoid tissue marginal zone lymphoma in a 46-year-old female: a case report.

IF 1.5 3区 医学 Q3 SURGERY
Gland surgery Pub Date : 2025-01-24 Epub Date: 2025-01-20 DOI:10.21037/gs-24-353
Jing Yang, Li Jiao, Guoli Du, Sheng Jiang
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引用次数: 0

Abstract

Background: Primary thyroid lymphoma (PTL) is an extremely rare form of thyroid malignancy, merely accounting for 2-5% of all cases. Owing to its low incidence and the absence of concrete clinical manifestations, PTL is frequently misdiagnosed as thyroiditis or thyroid cancer, thereby presenting a significant hurdle to accurate diagnosis.

Case description: This case study centered around a 46-year-old female patient. We meticulously detailed the diagnosis and treatment process of her primary thyroid mucosa-associated lymphoid tissue (MALT) marginal zone lymphoma. Although ultrasonography can preliminarily flag suspected cases, a histopathologic biopsy remains indispensable for a conclusive diagnosis. In terms of treatment, surgery is only recommended under specific circumstances. Radiotherapy and chemotherapy are common approaches and play a pivotal role in managing the conditions of particular PTL patients. In this instance, the patient sought medical attention due to a rapidly enlarging neck mass. Ultrasonography revealed diffuse thyroid lesions with reticular nodules, and further biopsy verified MALT lymphoma. Subsequently, an individualized radiotherapy plan was devised.

Conclusions: If PTL can be diagnosed at an early stage and treatment commenced promptly, the prognosis is generally favorable. Hence, a profound understanding of the clinical and imaging characteristics of PTL and the attainment of early diagnosis are of crucial importance for effective treatment and prognosis evaluation. This can not only enhance the survival rate of patients but also furnish valuable experience for the diagnosis and treatment of subsequent similar cases, facilitating the advancement of medicine.

46岁女性原发性甲状腺粘膜相关淋巴组织边缘区淋巴瘤1例。
背景:原发性甲状腺淋巴瘤(PTL)是一种极为罕见的甲状腺恶性肿瘤,仅占所有病例的2-5%。PTL发病率低,无具体临床表现,常被误诊为甲状腺炎或甲状腺癌,给准确诊断带来很大障碍。病例描述:本病例研究以一名46岁女性患者为中心。我们仔细详细的诊断和治疗过程的原发性甲状腺黏膜相关淋巴组织(MALT)边缘带淋巴瘤。虽然超声检查可以初步标记疑似病例,但组织病理活检对于结论性诊断仍然必不可少。在治疗方面,只有在特定情况下才建议进行手术。放疗和化疗是常见的方法,在治疗特殊PTL患者的情况中起着关键作用。在本例中,患者因颈部肿块迅速增大而求医。超声检查显示弥漫性甲状腺病变伴网状结节,进一步活检证实MALT淋巴瘤。随后,制定了个体化放疗计划。结论:如果PTL能够早期诊断并及时治疗,预后通常是良好的。因此,深入了解PTL的临床和影像学特征,实现早期诊断对有效治疗和预后评估至关重要。这不仅可以提高患者的生存率,而且可以为后续类似病例的诊断和治疗提供宝贵的经验,促进医学的进步。
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来源期刊
Gland surgery
Gland surgery Medicine-Surgery
CiteScore
3.60
自引率
0.00%
发文量
113
期刊介绍: Gland Surgery (Gland Surg; GS, Print ISSN 2227-684X; Online ISSN 2227-8575) being indexed by PubMed/PubMed Central, is an open access, peer-review journal launched at May of 2012, published bio-monthly since February 2015.
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