Facial metastasis of Esophageal squamous cell carcinoma

IF 2.3 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

American Journal of the Medical Sciences Pub Date : 2025-06-01 DOI:10.1016/j.amjms.2025.02.003

Sen-Ei Shai M.D. PhD. , Hung-Ju Kuo M.D. , Yi-Ling Lai M.S. , Chi-Wei Hsieh M.D.

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引用次数: 0

Abstract

Esophageal squamous cell carcinoma (SCC) is a highly lethal malignancy with a low survival rate, often presenting at an advanced stage. Cutaneous metastasis from esophageal SCC is exceedingly rare, affecting less than 1 % of cases, and is associated with a poor prognosis. This review particularly focuses on facial metastasis and discusses the clinical presentation, diagnostic challenges, and management of cutaneous metastases. The variability in clinical presentation often leads to misdiagnosis, delaying appropriate treatment. Histopathological examination and immunohistochemical staining are crucial for accurate diagnosis. Management involves a combination of local and systemic therapies, tailored to the patient's overall health and disease extent. This topic emphasizes the need for vigilance and thorough diagnostic workups in patients with unusual skin lesions and highlights the importance of multidisciplinary care in optimizing treatment outcomes for patients with advanced esophageal cancer.

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食管鳞状细胞癌的面部转移

食管鳞状细胞癌（SCC）是一种高致死性恶性肿瘤，生存率低，常在晚期出现。食管鳞状细胞癌的皮肤转移极为罕见，影响不到1%的病例，并且与预后不良有关。这篇综述特别关注面部转移，并讨论了临床表现、诊断挑战和皮肤转移的管理。临床表现的变化常常导致误诊，延误适当的治疗。组织病理学检查和免疫组织化学染色是准确诊断的关键。管理包括局部和全身治疗的结合，根据患者的整体健康和疾病程度量身定制。本主题强调了对异常皮肤病变患者保持警惕和彻底诊断的必要性，并强调了多学科护理在优化晚期食管癌患者治疗结果中的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of the Medical Sciences 医学-医学：内科

CiteScore

4.40

自引率

0.00%

发文量

303

审稿时长

1.5 months

期刊介绍： The American Journal of The Medical Sciences (AJMS), founded in 1820, is the 2nd oldest medical journal in the United States. The AJMS is the official journal of the Southern Society for Clinical Investigation (SSCI). The SSCI is dedicated to the advancement of medical research and the exchange of knowledge, information and ideas. Its members are committed to mentoring future generations of medical investigators and promoting careers in academic medicine. The AJMS publishes, on a monthly basis, peer-reviewed articles in the field of internal medicine and its subspecialties, which include: Original clinical and basic science investigations Review articles Online Images in the Medical Sciences Special Features Include: Patient-Centered Focused Reviews History of Medicine The Science of Medical Education.