Brief computer MI to motivate sustained tobacco cessation following psychiatric hospital discharge: Study protocol for a randomized controlled trial

IF 2 3区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Contemporary clinical trials Pub Date : 2025-02-10 DOI:10.1016/j.cct.2025.107841

Richard A. Brown , Abigail Winskowicz , David H. Johnson , Jacki Hecht , Jason Shumake , Kelly M. Carpenter , Julie Farrington , Jasper A.J. Smits

{"title":"Brief computer MI to motivate sustained tobacco cessation following psychiatric hospital discharge: Study protocol for a randomized controlled trial","authors":"Richard A. Brown , Abigail Winskowicz , David H. Johnson , Jacki Hecht , Jason Shumake , Kelly M. Carpenter , Julie Farrington , Jasper A.J. Smits","doi":"10.1016/j.cct.2025.107841","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Individuals with serious mental illness (SMI) smoke at disproportionately higher rates than those without SMI. We demonstrated, in a randomized controlled trial (RCT) of 342 adult smokers receiving inpatient psychiatric care, that an in-person, motivational interviewing (MI)-based, Sustained Care (SusC) intervention vs. Usual Care (UC) resulted in significantly higher rates of confirmed smoking abstinence at 6-months post-hospital discharge and significantly increased smoking cessation treatment utilization. While successful, this SusC intervention would be challenging to implement broadly in psychiatric hospitals. The current efficacy trial will develop and test an MI-based Sustained Care intervention delivered as a mobile app for iPad and will determine whether this approach can produce higher cessation rates compared to usual care for smokers admitted to a psychiatric inpatient unit.</div></div><div><h3>Methods</h3><div>A total of 250 eligible patients hospitalized for psychiatric illness will be randomized to: Tablet-delivered Sustained Care (T-SusC) or Usual Care (UC), and will be followed for six months after discharge. Participants assigned to UC will receive brief, in-hospital tobacco education. Those assigned to T-SusC will receive the brief tobacco education, plus a 40-min, in-hospital MI intervention delivered via a mobile application (app) for iPad use. They will also receive up to 8 weeks of free nicotine patches and a referral to the Texas Tobacco Quitline. Smoking cessation outcomes will be measured at 1-, 3- and 6-months post hospital discharge.</div></div><div><h3>Conclusion</h3><div>Results from this efficacy trial may add to our understanding of acceptable and effective smoking cessation approaches for patients hospitalized with SMI.</div></div>","PeriodicalId":10636,"journal":{"name":"Contemporary clinical trials","volume":"151 ","pages":"Article 107841"},"PeriodicalIF":2.0000,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contemporary clinical trials","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1551714425000357","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Individuals with serious mental illness (SMI) smoke at disproportionately higher rates than those without SMI. We demonstrated, in a randomized controlled trial (RCT) of 342 adult smokers receiving inpatient psychiatric care, that an in-person, motivational interviewing (MI)-based, Sustained Care (SusC) intervention vs. Usual Care (UC) resulted in significantly higher rates of confirmed smoking abstinence at 6-months post-hospital discharge and significantly increased smoking cessation treatment utilization. While successful, this SusC intervention would be challenging to implement broadly in psychiatric hospitals. The current efficacy trial will develop and test an MI-based Sustained Care intervention delivered as a mobile app for iPad and will determine whether this approach can produce higher cessation rates compared to usual care for smokers admitted to a psychiatric inpatient unit.

Methods

A total of 250 eligible patients hospitalized for psychiatric illness will be randomized to: Tablet-delivered Sustained Care (T-SusC) or Usual Care (UC), and will be followed for six months after discharge. Participants assigned to UC will receive brief, in-hospital tobacco education. Those assigned to T-SusC will receive the brief tobacco education, plus a 40-min, in-hospital MI intervention delivered via a mobile application (app) for iPad use. They will also receive up to 8 weeks of free nicotine patches and a referral to the Texas Tobacco Quitline. Smoking cessation outcomes will be measured at 1-, 3- and 6-months post hospital discharge.

Conclusion

Results from this efficacy trial may add to our understanding of acceptable and effective smoking cessation approaches for patients hospitalized with SMI.

查看原文本刊更多论文

简短的计算机MI激励精神病院出院后持续戒烟：随机对照试验的研究方案。

背景：重度精神疾病（SMI）患者的吸烟率比非重度精神疾病患者高得多。在一项随机对照试验（RCT）中，342名接受精神科住院治疗的成年吸烟者证明，面对面、动机访谈（MI）为基础的持续护理（SusC）干预与常规护理（UC）相比，在出院后6个月确诊的戒烟率显著提高，并显著增加戒烟治疗的使用率。虽然取得了成功，但在精神病院广泛实施这种可持续发展的干预措施将具有挑战性。目前的疗效试验将开发和测试一种基于mi的持续护理干预，作为iPad的移动应用程序提供，并将确定这种方法是否能产生更高的戒烟率，与常规护理相比，接受精神科住院治疗的吸烟者。方法：共有250名符合条件的精神疾病住院患者将被随机分配到：片剂持续护理（T-SusC）或常规护理（UC），并在出院后随访6个月。分配到UC的参与者将接受简短的住院烟草教育。那些被分配到T-SusC的人将接受简短的烟草教育，外加通过iPad移动应用程序提供的40分钟的院内心肌梗死干预。他们还将获得长达8 周的免费尼古丁贴片，并被推荐到德克萨斯州烟草戒烟热线。戒烟结果将在出院后1、3和6个月进行测量。结论：这项疗效试验的结果可能增加我们对重度精神分裂症住院患者可接受和有效的戒烟方法的理解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Contemporary clinical trials 医学-药学

CiteScore

3.70

自引率

4.50%

发文量

281

审稿时长

44 days

期刊介绍： Contemporary Clinical Trials is an international peer reviewed journal that publishes manuscripts pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from disciplines including medicine, biostatistics, epidemiology, computer science, management science, behavioural science, pharmaceutical science, and bioethics. Full-length papers and short communications not exceeding 1,500 words, as well as systemic reviews of clinical trials and methodologies will be published. Perspectives/commentaries on current issues and the impact of clinical trials on the practice of medicine and health policy are also welcome.