Progressive Myelitis in a 63-Year-Old Woman: A Case Report From the National Multiple Sclerosis Society Case Conference Proceedings.

IF 7.8 1区医学 Q1 CLINICAL NEUROLOGY

Neurology® Neuroimmunology & Neuroinflammation Pub Date : 2025-03-01 Epub Date: 2025-02-10 DOI:10.1212/NXI.0000000000200382

Kimberly A DiMauro, Morgan E Heber, Jonathan Lee, Jeffrey A Cohen, Eoin P Flanagan, Claire Riley, Myla D Goldman, Scott S Zamvil, Amy C Kunchok

引用次数: 0

Abstract

We present a case of myelitis in a 63-year-old woman with breast adenocarcinoma treated with pembrolizumab. MRI showed multiple T2-hyperintense lesions throughout the spinal cord, and CSF demonstrated lymphocytic pleocytosis. We discuss the differential diagnosis of myelitis in the setting of cancer and immune checkpoint inhibitors.

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一名63岁妇女的进行性脊髓炎：来自全国多发性硬化症协会病例会议记录的病例报告。

我们提出一例脊髓炎，在63岁的妇女与乳腺腺癌与派姆单抗治疗。MRI显示脊髓多发t2高信号病变，脑脊液显示淋巴细胞增多。我们讨论脊髓炎的鉴别诊断在设置癌症和免疫检查点抑制剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurology® Neuroimmunology & Neuroinflammation Neuroscience-Neurology

CiteScore

15.60

自引率

2.30%

发文量

219

审稿时长

8 weeks

期刊介绍： Neurology Neuroimmunology & Neuroinflammation is an official journal of the American Academy of Neurology. Neurology: Neuroimmunology & Neuroinflammation will be the premier peer-reviewed journal in neuroimmunology and neuroinflammation. This journal publishes rigorously peer-reviewed open-access reports of original research and in-depth reviews of topics in neuroimmunology & neuroinflammation, affecting the full range of neurologic diseases including (but not limited to) Alzheimer's disease, Parkinson's disease, ALS, tauopathy, and stroke; multiple sclerosis and NMO; inflammatory peripheral nerve and muscle disease, Guillain-Barré and myasthenia gravis; nervous system infection; paraneoplastic syndromes, noninfectious encephalitides and other antibody-mediated disorders; and psychiatric and neurodevelopmental disorders. Clinical trials, instructive case reports, and small case series will also be featured.