Use of intraoperative ultrasound in differentiating adamantinomatous versus papillary craniopharyngiomas and guiding resection through the endoscopic endonasal route
Chandrima Biswas, Moataz D. Abouammo, Ludovica Pasquini, Guilherme Mansur, Mohammad Bilal Alsavaf, Kyle C. Wu, Ricardo L. Carrau, Daniel M. Prevedello
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引用次数: 0
Abstract
Craniopharyngiomas (CPs) are surgically challenging tumors. The prevalence of BRAF mutation in papillary craniopharyngioma (PCP) and the positive response with BRAF-MEK inhibitors have shifted the treatment paradigm towards targeted therapy. However, maximal safe resection remains the goal, particularly for adamantinomatous craniopharyngioma (ACP). In this report, we describe two cases of CP where intraoperative ultrasonography (IOUS) was helpful in differentiating the subtype of CP, thus enabling intraoperative decision-making regarding the extent of resection. Additionally, IOUS images of three more (two PCP and one ACP) patients who underwent endoscopic endonasal resection for CPs were retrospectively evaluated. Each of these entities showed characteristic appearances on IOUS.
期刊介绍：
The journal "Acta Neurochirurgica" publishes only original papers useful both to research and clinical work. Papers should deal with clinical neurosurgery - diagnosis and diagnostic techniques, operative surgery and results, postoperative treatment - or with research work in neuroscience if the underlying questions or the results are of neurosurgical interest. Reports on congresses are given in brief accounts. As official organ of the European Association of Neurosurgical Societies the journal publishes all announcements of the E.A.N.S. and reports on the activities of its member societies. Only contributions written in English will be accepted.
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