Neuro-oncological research output in the Middle East: A scoping review

Q3 Medicine

Cancer treatment and research communications Pub Date : 2024-01-01 DOI:10.1016/j.ctarc.2025.100883

Ibraheem M. Alkhawaldeh , Mohammad Al-Jafari , Mostafa Hossam El din Moawad , Yasmeen Jamal Alabdallat , Mahmoud Shaaban Abdelgalil , Amro K. AlQurm , Sadeen Zein Eddin , Layan H. Darwish , Hamza K. Alsalhi , Safa G. Odeh , Abdulqadir J. Nashwan , Ahmad A. Abujaber

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引用次数: 0

Abstract

Background

The current research efforts in the Middle East do not sufficiently capture the full extent of the burden posed by brain tumors in the region.

Objective

Our study aimed to investigate the present state and future prospects of neuro-oncological research in the Middle East, with a focus on addressing existing research gaps.

Methods

We conducted a comprehensive literature search on brain tumors in the Middle East, utilizing PubMed, Scopus, and Web of Science databases. Data extraction was performed by a team of four authors using Microsoft Excel. We categorized studies based on research type, study design, subject matter, and author collaboration. Statistical analysis was conducted using RStudio 4.2.3 for categorical variables, and charts and figures were generated using RStudio 4.2.3 and Microsoft Excel version 16.

Results

Our scoping review analyzed 1,451 research articles related to Central Nervous System (CNS) tumors. Primary research accounted for 65.3 % of the studies, secondary research for 11.4 %, and other research types for 23.3 %. Turkish and Iranian authors played a significant role in primary research. Case reports (23.7 %) and retrospective studies (15.9 %) were the most common study designs. Clinical studies constituted the majority (89.5 %), with public health (2.75 %) and experimental studies (7.75 %) forming the rest. Gliomas were the most prevalent CNS tumor type (20.7 %), followed by astrocytomas (6.8 %) and meningiomas (6.2 %).

Conclusion

To meet the increasing demands of researchers, improved access to high-quality neurosurgical programs and centers in the Middle East is essential. Inadequate institutional planning may contribute to the current research accessibility deficits.

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中东地区的神经肿瘤研究成果：范围审查

背景目前在中东的研究工作并没有充分反映该地区脑肿瘤造成的负担的全部程度。目的本研究旨在探讨中东地区神经肿瘤学研究的现状和未来前景，重点解决现有的研究空白。方法利用PubMed、Scopus和Web of Science数据库，对中东地区脑肿瘤进行文献检索。数据提取由四名作者组成的团队使用Microsoft Excel进行。我们根据研究类型、研究设计、主题和作者合作对研究进行分类。分类变量使用RStudio 4.2.3进行统计分析，图表和图形使用RStudio 4.2.3和Microsoft Excel version 16生成。结果本综述分析了1451篇与中枢神经系统（CNS）肿瘤相关的研究论文。主要研究占65.3%，次要研究占11.4%，其他研究占23.3%。土耳其和伊朗作者在初级研究中发挥了重要作用。病例报告（23.7%）和回顾性研究（15.9%）是最常见的研究设计。临床研究占多数（89.5%），其余为公共卫生研究（2.75%）和实验研究（7.75%）。神经胶质瘤是最常见的中枢神经系统肿瘤类型（20.7%），其次是星形细胞瘤（6.8%）和脑膜瘤（6.2%）。结论为满足研究人员日益增长的需求，提高中东地区高质量神经外科项目和中心的可及性至关重要。机构规划不足可能导致目前的研究可及性不足。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer treatment and research communications Medicine-Oncology

CiteScore

4.30

自引率

0.00%

发文量

148

审稿时长

56 days

期刊介绍： Cancer Treatment and Research Communications is an international peer-reviewed publication dedicated to providing comprehensive basic, translational, and clinical oncology research. The journal is devoted to articles on detection, diagnosis, prevention, policy, and treatment of cancer and provides a global forum for the nurturing and development of future generations of oncology scientists. Cancer Treatment and Research Communications publishes comprehensive reviews and original studies describing various aspects of basic through clinical research of all tumor types. The journal also accepts clinical studies in oncology, with an emphasis on prospective early phase clinical trials. Specific areas of interest include basic, translational, and clinical research and mechanistic approaches; cancer biology; molecular carcinogenesis; genetics and genomics; stem cell and developmental biology; immunology; molecular and cellular oncology; systems biology; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; cancer policy; and integration of various approaches. Our mission is to be the premier source of relevant information through promoting excellence in research and facilitating the timely translation of that science to health care and clinical practice.