Validation of A Nationwide Digital Pediatric Pathology Consultation Network.

IF 1.3 4区医学 Q3 PATHOLOGY

Pediatric and Developmental Pathology Pub Date : 2025-05-01 Epub Date: 2025-02-10 DOI:10.1177/10935266251316782

Haiying Chen, Juan Putra, Anita Nagy, Jefferson Terry, Dina El Demellawy, Joseph de Nanassy, Erica Schollenberg, Aaron Haig, Camelia Stefanovici, Kathryn Whelan, Alysa Poulin, Dorothee Dal Soglio, Zesheng Chen, Brian Smith, Cindy Fiore, Gino R Somers

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引用次数: 0

Abstract

Background: Digital pathology facilitates remote pathology consultations. Pediatric pathologists in Canada formed a nationwide digital pathology consultation network, mostly for second opinion review of pediatric cancer cases. Validation of such a large network for clinical use is challenging. Here we report our unique validation process of this digital pathology network.

Method: This study was designed in keeping with the College of American Pathologist (CAP) guidelines, and included 14 pathologists from 9 hospitals across Canada. All cases are pediatric pathology cases. Each pathologist reviewed multiple digital cases and the corresponding glass slide cases. For each review, intra-observer concordance (diagnosis on digital case versus diagnosis on glass slide case) was recorded, creating a data point.

Result: The study generated 269 valid diagnostic data points. Out of the 269 data points, 257 were concordant (95.5% concordance), exceeding the CAP recommendation of 95% concordance. Thus, the network was successfully validated.

Conclusion: This is a unique validation study for a large nationwide digital pediatric pathology network. The study involved all pathologists/hospitals in the network, closely emulating real world clinical process. The network was successfully validated.

Abstract Image

查看原文本刊更多论文

全国数字儿科病理咨询网络的验证。

背景：数字病理学促进了远程病理会诊。加拿大的儿科病理学家形成了一个全国性的数字病理咨询网络，主要用于儿科癌症病例的第二意见审查。验证如此庞大的网络用于临床应用是具有挑战性的。在这里，我们报告了我们对这个数字病理网络的独特验证过程。方法：本研究是按照美国病理学家学会（CAP）的指南设计的，包括来自加拿大9家医院的14名病理学家。所有病例均为小儿病理病例。每位病理学家回顾了多个数字病例和相应的玻片病例。对于每次回顾，记录观察者内部的一致性（数字病例的诊断与玻片病例的诊断），创建一个数据点。结果：该研究产生了269个有效的诊断数据点。269个数据点中，257个数据点一致（95.5%），超过CAP推荐的95%一致性。因此，网络验证成功。结论：这是一项针对大型全国性数字儿科病理网络的独特验证研究。该研究涉及网络中的所有病理学家/医院，密切模仿现实世界的临床过程。日志含义网络验证成功。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric and Developmental Pathology 医学-病理学

CiteScore

3.70

自引率

5.30%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal covers the spectrum of disorders of early development (including embryology, placentology, and teratology), gestational and perinatal diseases, and all diseases of childhood. Studies may be in any field of experimental, anatomic, or clinical pathology, including molecular pathology. Case reports are published only if they provide new insights into disease mechanisms or new information.