Synechism 2.0: Contours of a new theory of continuity in bioengineering

Abstract

The methodological principle of synechism, the all-pervading continuity first proposed by Charles Peirce in 1892, is reinvigorated in the present paper to prompt a comprehensive reevaluation of the integrated concepts of life, machines, agency, and intelligence. The evidence comes from the intersections of synthetic bioengineering, developmental biology, and cognitive and computational sciences. As a regulative principle, synechism, “that continuity governs the whole domain of experience in every element of it”, has been shown to infiltrate fundamental issues of contemporary biology, including cognition in different substrates, embodied agency, collectives (swarm and nested), intelligence on multiple scales, and developmental bioelectricity in morphogenesis. In the present paper, we make explicit modern biology's turn to this fundamental feature of science in its rejection of conceptual binaries, preference for collectives over individuals, quantitative over qualitative, and multiscale applicability of the emerging hypotheses about the integration of the first principles of the diversity of life. Specifically, synechism presents itself as the bedrock for research encompassing biological machines, chimaeras, organoids, and Xenobots. We then review a synechistic framework that embeds functionalist, information-theoretic, pragmaticist and inferentialist approaches to springboard to continuum-driven biosystemic behaviour.