Unusual brain metastasis from colon cancer.

Surgical neurology international Pub Date : 2025-01-03 eCollection Date: 2025-01-01 DOI:10.25259/SNI_636_2024
John Vargas-Urbina, Raúl Martinez-Silva, Giuseppe Rojas-Panta, Gabriel Ponce-Manrique, Jerson Flores-Castillo, William Anicama-Lima
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Abstract

Background: Brain metastases due to colorectal cancer correspond to 3-5% of all brain metastases. The prognostic factors are based on age, functional status, and single metastasis. Its management is multidisciplinary, with poor prognosis despite the management.

Case description: A case of a 64-year-old male presented with symptoms of headache, disorientation, and nausea. The enhanced magnetic resonance image showed a mass in the right frontal horn of the lateral ventricle, contrast enhancing, with irregular borders, but defined, without restriction in diffusion-weighted images, associated with obstructive hydrocephalus. The investigations in search of a primary neoplasm were negative. A ventricular endoscopic approach was performed, with total resection of the lesion. Four months later, he developed a bowel obstruction with surgical management to control the primary, followed by chemotherapy and radiotherapy, with a current survival longer than 1 year.

Conclusion: Brain metastases due to colorectal cancer are rare, and usually, when diagnosed, there are already pulmonary and hepatic metastases. Multidisciplinary management is recommended, where surgical management can be included in selected cases with controlled systemic disease, good functional condition, and single metastasis.

不寻常的结肠癌脑转移。
背景:结直肠癌引起的脑转移占所有脑转移的3-5%。预后因素基于年龄、功能状态和单次转移。其治疗是多学科的,治疗后预后较差。病例描述:一例64岁男性,表现为头痛、定向障碍和恶心。增强磁共振图像显示侧脑室右额角肿块,对比度增强,边界不规则,但边界明确,在弥散加权图像上没有限制,与阻塞性脑积水有关。寻找原发肿瘤的调查结果为阴性。采用脑室内窥镜入路,完全切除病变。4个月后,患者发生肠梗阻,手术控制原发,随后化疗和放疗,目前生存期超过1年。结论:结直肠癌脑转移罕见,确诊时通常已存在肺、肝转移。推荐多学科治疗,选择全身性疾病控制、功能状况良好、单一转移的病例进行手术治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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