Elizabeth L. Ciemins PhD, MPH, MA (is Senior Vice President, Research and Analytics, American Medical Group Association (AMGA), Alexandria, Virginia), Cori C. Grant PhD, MBA, MS (is Research Assistant Professor, College of Liberal Arts and Social Sciences and Department of Health Systems and Population Health, University of Houston), Meghana Tallam MPH (is Population Health Research Analyst, AMGA), Cori Rattelman MS (is Senior Research Analyst, AMGA), Curt Lindberg DMan, MHA (is Principal and Senior Consultant, Partners in Complexity, Waitsfield, Vermont), Rae Ann Williams MD, FACP (is Department Chair, Internal Medicine, and Regional Medical Director, Primary Care, HealthPartners Medical Group, Bloomington, Minnesota), Paige S. Christensen NP (is Associate Medical Director, Thrombosis and Anticoagulation, and Director, Clinical Pharmacy Anticoagulation Service, Intermountain Healthcare, Salt Lake City), N. Marcus Thygeson MD, MPH (is Executive Director, Adaptive Health, San Rafael, California. Please address correspondence to Elizabeth L. Ciemins)
{"title":"Using Implementation Science-Informed Strategies to Improve Transitions of Care for Patients with Venous Thromboembolism","authors":"Elizabeth L. Ciemins PhD, MPH, MA (is Senior Vice President, Research and Analytics, American Medical Group Association (AMGA), Alexandria, Virginia), Cori C. Grant PhD, MBA, MS (is Research Assistant Professor, College of Liberal Arts and Social Sciences and Department of Health Systems and Population Health, University of Houston), Meghana Tallam MPH (is Population Health Research Analyst, AMGA), Cori Rattelman MS (is Senior Research Analyst, AMGA), Curt Lindberg DMan, MHA (is Principal and Senior Consultant, Partners in Complexity, Waitsfield, Vermont), Rae Ann Williams MD, FACP (is Department Chair, Internal Medicine, and Regional Medical Director, Primary Care, HealthPartners Medical Group, Bloomington, Minnesota), Paige S. Christensen NP (is Associate Medical Director, Thrombosis and Anticoagulation, and Director, Clinical Pharmacy Anticoagulation Service, Intermountain Healthcare, Salt Lake City), N. Marcus Thygeson MD, MPH (is Executive Director, Adaptive Health, San Rafael, California. Please address correspondence to Elizabeth L. Ciemins)","doi":"10.1016/j.jcjq.2024.12.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, are common causes of preventable hospital death. Most VTEs diagnosed in the outpatient setting are directly linked to a recent hospitalization or surgery.</div></div><div><h3>Methods</h3><div>A type 2 effectiveness-implementation hybrid study was conducted to develop and implement targeted interventions to improve care for patients with VTE in six US health systems. Primary outcomes included (1) 7-day follow-up after VTE diagnosis (phone calls, office visits); (2) VTE–related hospitalizations or emergency department (ED) visits within 45 days of acute VTE diagnosis; and (3) anticoagulant-associated adverse drug events (ADEs). Qualitative comparative analysis (QCA) identified interventions associated with improved care for patients with VTE.</div></div><div><h3>Results</h3><div>Among 1,265 patients, follow-up within 7 days of an index VTE diagnosis improved from 25.2% to 33.6% (<em>p</em> < 0.0001); among 2,002 patients, hospitalizations/ED visits within 45 days of VTE diagnosis decreased across settings from 7.8% to 6.3% (<em>p</em> = 0.033), and the rate of anticoagulant-associated ADEs remained low (3.1% to 3.4%, <em>p</em> = 0.528). Factors characteristic of improving 7-day follow-up included combinations of (1) safer prescribing and management of anticoagulants and standardized protocols with centralized care processes or (2) safer prescribing and management of anticoagulants with improved care team communication and expanded anticoagulation clinic access for patients prescribed direct oral anticoagulants. Factors associated with 45-day hospitalization/ED visits improvement included high baseline rates of 7-day follow-up, high rates of baseline 45-day hospitalization/ED visits (larger opportunity), improved care team communication, and improved standardization and centralization of protocols.</div></div><div><h3>Conclusion</h3><div>Combinations of interventions, tailored to local context and team dynamics, improved ambulatory follow-up rates and reduced VTE–related utilization. Health systems may benefit from considering novel, implementation science–informed strategies to foster improvement.</div></div>","PeriodicalId":14835,"journal":{"name":"Joint Commission journal on quality and patient safety","volume":"51 4","pages":"Pages 241-251"},"PeriodicalIF":2.3000,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Joint Commission journal on quality and patient safety","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1553725024004021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, are common causes of preventable hospital death. Most VTEs diagnosed in the outpatient setting are directly linked to a recent hospitalization or surgery.
Methods
A type 2 effectiveness-implementation hybrid study was conducted to develop and implement targeted interventions to improve care for patients with VTE in six US health systems. Primary outcomes included (1) 7-day follow-up after VTE diagnosis (phone calls, office visits); (2) VTE–related hospitalizations or emergency department (ED) visits within 45 days of acute VTE diagnosis; and (3) anticoagulant-associated adverse drug events (ADEs). Qualitative comparative analysis (QCA) identified interventions associated with improved care for patients with VTE.
Results
Among 1,265 patients, follow-up within 7 days of an index VTE diagnosis improved from 25.2% to 33.6% (p < 0.0001); among 2,002 patients, hospitalizations/ED visits within 45 days of VTE diagnosis decreased across settings from 7.8% to 6.3% (p = 0.033), and the rate of anticoagulant-associated ADEs remained low (3.1% to 3.4%, p = 0.528). Factors characteristic of improving 7-day follow-up included combinations of (1) safer prescribing and management of anticoagulants and standardized protocols with centralized care processes or (2) safer prescribing and management of anticoagulants with improved care team communication and expanded anticoagulation clinic access for patients prescribed direct oral anticoagulants. Factors associated with 45-day hospitalization/ED visits improvement included high baseline rates of 7-day follow-up, high rates of baseline 45-day hospitalization/ED visits (larger opportunity), improved care team communication, and improved standardization and centralization of protocols.
Conclusion
Combinations of interventions, tailored to local context and team dynamics, improved ambulatory follow-up rates and reduced VTE–related utilization. Health systems may benefit from considering novel, implementation science–informed strategies to foster improvement.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
