A novel electrochemical sensor for vitamin D3 detection in real samples using NiNPs-ZIF-8-modified electrode

IF 2.8 3区化学 Q3 CHEMISTRY, PHYSICAL

Chemical Physics Letters Pub Date : 2025-02-03 DOI:10.1016/j.cplett.2025.141936

Konda Bindu , Tummala Anusha , Pradeep Kumar Brahman

引用次数: 0

Abstract

A highly sensitive sensing platform based on nickel nanoparticles (NiNPs) and zeolitic imidazolate framework-8 (ZIF-8) was synthesized for quantitative measurement of vitamin D₃. The physical characteristics and behaviour of the fabricated electrode were investigated using various surface and electrochemical techniques. Under optimal conditions, the NiNPs-ZIF-8@GCE demonstrated a broad dynamic range from 0.025 to 25 μM with a detection limit of 0.002 μM. Moreover, the ultrasensitive vitamin D₃ sensor displayed acceptable reproducibility, satisfactory specificity, good storage stability, and high sensitivity. Ultimately, the proposed sensor successfully detects various concentrations of vitamin D₃ in biological samples, affirming its practical applicability.

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来源期刊

Chemical Physics Letters 化学-物理：原子、分子和化学物理

CiteScore

5.70

自引率

3.60%

发文量

798

审稿时长

33 days

期刊介绍： Chemical Physics Letters has an open access mirror journal, Chemical Physics Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Chemical Physics Letters publishes brief reports on molecules, interfaces, condensed phases, nanomaterials and nanostructures, polymers, biomolecular systems, and energy conversion and storage. Criteria for publication are quality, urgency and impact. Further, experimental results reported in the journal have direct relevance for theory, and theoretical developments or non-routine computations relate directly to experiment. Manuscripts must satisfy these criteria and should not be minor extensions of previous work.