Psychometric properties of patient-reported outcomes measurement information system (PROMIS) fixed short forms in Juvenile Myositis

IF 4.6 2区医学 Q1 RHEUMATOLOGY

Seminars in arthritis and rheumatism Pub Date : 2025-02-01 DOI:10.1016/j.semarthrit.2025.152649

Kaveh Ardalan , Mariana C. Marques , David Cella , Megan L. Curran , Elizabeth L. Gray , Jungwha Lee , Kyle J. Fahey , Madison L. Wolfe , Lauren M. Pachman , Rowland W. Chang

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引用次数: 0

Abstract

Objectives

Assess reliability and validity of Patient-Reported Outcomes Measurement Information System (PROMIS) pediatric self-report and parent-proxy report fixed short forms in juvenile myositis (JM).

Methods

Children with JM (8–17yo) and parents of 5–17 yo JM patients completed PROMIS measures (Physical Function, Pain Interference, Fatigue, Emotional Distress), PedsQL Generic Core scales and Rheumatology Module (PedsQL-GC/-RM). Internal consistency reliability was assessed via Cronbach's alpha. Patient-parent agreement was assessed via intraclass correlations (ICC). Concurrent and construct validity were assessed via Spearman's correlations between PROMIS versus PedsQL-GC/-RM and clinical/lab data respectively. Known-groups validity was assessed by comparing PROMIS T-scores between clinically distinct JM patients.

Results

We enrolled 75 JM participants, with 57 administered self-report and all 75 administered parent-proxy report measures per participant age. PROMIS measures were feasible (>96% completion), with high internal consistency reliability (Cronbach's alpha >0.8). Patient-parent assessments demonstrated moderate agreement (ICC >0.5) for Mobility, Upper Extremity, and Fatigue domains, and smaller correlations (ICC 0.41–0.47) as expected for Pain Interference, Depressive Symptoms, and Anxiety. Concurrent validity was demonstrated by moderate correlation (Spearman's rho >0.5) for all but 1 hypothesized relationships of PROMIS and PedsQL-GC/-RM domains. Although low disease activity and small sample size limited statistical power, construct validity and known-groups validity were demonstrable for multiple PROMIS pediatric self-report and parent-proxy report measures.

Conclusion

PROMIS measures show evidence of reliability and validity in JM. Child and parent reports differ sufficiently to suggest both should be collected. PROMIS measures can be considered for clinical and research use in JM.

查看原文本刊更多论文

青少年肌炎患者报告结果测量信息系统（PROMIS）固定短表格的心理测量特性

目的评估患者报告结局测量信息系统（PROMIS）儿童自我报告和家长代理报告固定短表在青少年肌炎（JM）中的信度和效度。方法JM患儿（8 - 17岁）和5-17岁JM患者的家长完成PROMIS测量（身体功能、疼痛干扰、疲劳、情绪困扰）、PedsQL通用核心量表和风湿病学模块（PedsQL- gc /-RM）。内部一致性信度采用Cronbach’s alpha评估。通过组内相关性（ICC）评估患者-家长协议。并发效度和结构效度分别通过PROMIS与PedsQL-GC/-RM之间的Spearman相关性和临床/实验室数据进行评估。通过比较临床不同JM患者的PROMIS t评分来评估已知组效度。结果：我们招募了75名JM参与者，其中57人接受自我报告，75人接受父母代理报告。PROMIS措施是可行的（96%的完成率），具有较高的内部一致性信度（Cronbach's alpha >0.8）。患者-家长评估显示，在活动能力、上肢和疲劳方面有中等程度的一致性（ICC >0.5），而在疼痛干扰、抑郁症状和焦虑方面的相关性较小（ICC 0.41-0.47）。除了1个假设关系外，PROMIS和PedsQL-GC/-RM域的所有假设关系都具有中等相关性（Spearman's rho >0.5），证明了并发效度。虽然低疾病活动性和小样本量限制了统计效力，但对于多个PROMIS儿童自我报告和父母代理报告测量，结构效度和已知组效度是可以证明的。结论promis量表在JM中具有一定的信度和效度。儿童和家长的报告差异很大，因此建议应收集两者的报告。可以考虑将PROMIS措施用于JM的临床和研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in arthritis and rheumatism 医学-风湿病学

CiteScore

9.20

自引率

4.00%

发文量

176

审稿时长

46 days

期刊介绍： Seminars in Arthritis and Rheumatism provides access to the highest-quality clinical, therapeutic and translational research about arthritis, rheumatology and musculoskeletal disorders that affect the joints and connective tissue. Each bimonthly issue includes articles giving you the latest diagnostic criteria, consensus statements, systematic reviews and meta-analyses as well as clinical and translational research studies. Read this journal for the latest groundbreaking research and to gain insights from scientists and clinicians on the management and treatment of musculoskeletal and autoimmune rheumatologic diseases. The journal is of interest to rheumatologists, orthopedic surgeons, internal medicine physicians, immunologists and specialists in bone and mineral metabolism.