Chinese reference population: Open-source age-dependent computational phantoms of reference Chinese population

IF 3.2 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Medical physics Pub Date : 2025-02-07 DOI:10.1002/mp.17670

Siyi Huang, Qian Liu, Tianwu Xie

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引用次数: 0

Abstract

Purpose

Computational phantoms have been widely used in radiation protection, radiotherapy, medical imaging, surgery navigation, and digital anatomy. However, current Chinese phantoms lack representation for all sensitive groups including adults, children, and pregnant women. This manuscript aims to address this gap by developing novel open-access computational phantoms representing the Chinese population.

Acquisition and validation methods

The Chinese reference population (CRP) developed in this study includes 30 phantoms, available in both voxel and nonuniform rational B-spline (NURBS) formats, with ages in 0, 1, 2, 3, 4, 5, 6, 8, 10, 12, 15, 18 years, and adult male and female, as well as four pregnant women in early pregnancy, first trimester, second trimester, and third trimester. The development process involved image segmentation, NURBS reconstruction, and voxelization based on whole-body computed tomography (CT) scans of 22 original individual patients. Reference organ masses were directly obtained from the Chinese Reference Human Anatomical Physiological and Metabolic Data, as well as international commission on radiological protection (ICRP) Publication 89.

Data format and usage notes

Voxelized phantoms are accessible in DAT format as raw data, which can be opened by medical imaging softwares such as a medical image data analysis tool (AMIDE). Excel files contain descriptive information (ages, genders, phantom sizes, voxel sizes, organ masses, densities) and organ absorbed doses on $^{18} F - F D G$ application. All data in this study can be obtained from our official website (https://alldigitaltwins.com) and Zenodo (https://zenodo.org/records/14268606).

Potential applications

This work offers a collection of open-source age-dependent phantoms featuring anatomical data specific to the Chinese population. Researchers can utilize this dataset to modify and adapt the phantoms for specific applications, fostering innovation and progress, and enhancing accuracy and applicability in various fields.

查看原文本刊更多论文

中国参考人口：开放源码的中国参考人口年龄依赖计算模型。

目的：计算幻影在放射防护、放射治疗、医学影像、手术导航、数字解剖等领域有着广泛的应用。然而，目前的中国幽灵缺乏对所有敏感群体的代表，包括成人、儿童和孕妇。本文旨在通过开发代表中国人口的新型开放获取计算模型来解决这一差距。获取和验证方法：本研究中开发的中国参考人群（CRP）包括30个幻像，有体素和非均匀理性b样条（NURBS）格式，年龄分别为0、1、2、3、4、5、6、8、10、12、15、18岁，成年男性和女性，以及4名妊娠早期、妊娠早期、妊娠中期和妊娠晚期的孕妇。开发过程包括图像分割、NURBS重建和基于22例原始个体患者全身计算机断层扫描（CT）的体素化。参考器官肿块直接取自《中国人体解剖生理代谢参考资料》和国际放射防护委员会（ICRP）第89号出版物。数据格式和使用说明：体素化的幻影以DAT格式作为原始数据访问，可通过医学成像软件（如医学图像数据分析工具（AMIDE））打开。Excel文件包含描述性信息（年龄，性别，幻体大小，体素大小，器官质量，密度）和器官吸收剂量在18f - fdg$ ^{18}F- fdg $应用。本研究的所有数据都可以从我们的官方网站（https://alldigitaltwins.com）和Zenodo (https://zenodo.org/records/14268606).Potential)应用程序中获得。这项工作提供了一组开源的年龄相关模型，其中包括中国人口的特定解剖数据。研究人员可以利用这个数据集来修改和适应特定的应用，促进创新和进步，提高在各个领域的准确性和适用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medical physics 医学-核医学

CiteScore

6.80

自引率

15.80%

发文量

660

审稿时长

1.7 months

期刊介绍： Medical Physics publishes original, high impact physics, imaging science, and engineering research that advances patient diagnosis and therapy through contributions in 1) Basic science developments with high potential for clinical translation 2) Clinical applications of cutting edge engineering and physics innovations 3) Broadly applicable and innovative clinical physics developments Medical Physics is a journal of global scope and reach. By publishing in Medical Physics your research will reach an international, multidisciplinary audience including practicing medical physicists as well as physics- and engineering based translational scientists. We work closely with authors of promising articles to improve their quality.