Daniel J Berman, Alexander W Mahler, Ryan C Burke, Andrew E Bennett, Nathan I Shapiro, Leslie A Bilello
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引用次数: 0
Abstract
Objectives: Management strategies for small bowel obstruction (SBO) vary from conservative approaches to surgical intervention. A known complication of surgery is the subsequent adhesions that can cause recurrent SBOs, longer hospital stays, and higher treatment costs. Our primary outcome was to identify independent risk factors that are associated with the decision for surgical intervention, and our secondary outcome was to describe characteristics of visits associated with complications.
Methods: This study was a single-center, retrospective chart review from a large, urban university hospital. We included adult patients admitted to the emergency department (ED) with the International Classification of Diseases, 10th Rev, codes for small bowel obstruction from June 1, 2017- May 30, 2019. Eligible covariates were demographics, radiological findings, clinical presentation, past medical history, and results of radiologic testing. We identified univariate associations of outcome and then performed a multivariate logistic regression to identify independent associations of each outcome. Finally, a backwards selection was used to determine the final model. We calculated odds ratios (OR) and 95% confidence intervals (CI) along with the area under the curve (AUC), as appropriate.
Results: A total of 530 patients met the study criteria; 148 (27.9%) underwent surgery of whom 35 (6.6%) had complications. We identified seven independent associations for the decision of surgery: abdominal distension (OR 0.27, 95% CI 0.10-0.62); gastrografin (OR 0.41, 95% CI 0.20-0.81); previous SBO (OR 0.42, 95% CI 0.26-0.66); higher Charlson Comorbidity Index score (OR 0.87, 95% CI 0.80-0.95); nasogastric decompression (OR 2.04, 95% CI 1.25-3.39), initial systolic blood pressure <100 mm Hg (OR 2.65, 95% CI 1.05-6.53); free fluid or volvulus/closed-loop obstruction on computed tomography (OR 7.95, 95% CI 4.25-15.39), with the AUC for the predictive model equaling 0.73.
Conclusion: We identified seven independent associations present in the ED associated with the decision for surgery. These associations are a step toward building better prediction models and improving decision-making in the ED, allowing for a more adequate treatment plan.
目的:小肠梗阻(SBO)的治疗策略从保守入路到手术干预各不相同。手术的一个已知并发症是随后的粘连,可引起复发性sbo、更长的住院时间和更高的治疗费用。我们的主要结果是确定与手术干预决定相关的独立危险因素,我们的次要结果是描述与并发症相关的就诊特征。方法:本研究为单中心、回顾性图表分析,来自一所大型城市大学医院。我们纳入了2017年6月1日至2019年5月30日期间在急诊科(ED)接受国际疾病分类(International Classification of Diseases, 10th Rev)编码的小肠阻塞成年患者。符合条件的协变量包括人口统计学、放射学表现、临床表现、既往病史和放射学检测结果。我们确定了结果的单变量关联,然后进行了多变量逻辑回归来确定每个结果的独立关联。最后,通过反向选择来确定最终模型。我们计算了比值比(OR)和95%置信区间(CI)以及曲线下面积(AUC)。结果:530例患者符合研究标准;其中手术148例(27.9%),并发症35例(6.6%)。我们确定了7个与手术决定相关的独立因素:腹胀(OR 0.27, 95% CI 0.10-0.62);胃grafin (OR 0.41, 95% CI 0.20-0.81);既往SBO (OR 0.42, 95% CI 0.26-0.66);较高的Charlson合并症指数评分(OR 0.87, 95% CI 0.80-0.95);结论:我们确定了与手术决定相关的ED中存在的7个独立关联。这些关联是朝着建立更好的预测模型和改善ED的决策迈出的一步,允许更充分的治疗计划。
期刊介绍:
WestJEM focuses on how the systems and delivery of emergency care affects health, health disparities, and health outcomes in communities and populations worldwide, including the impact of social conditions on the composition of patients seeking care in emergency departments.