Effects of needling at Sanyinjiao (SP6) acupuncture point on blood glucose levels and cardiovascular functions in patients with type 2 diabetes mellitus: a randomized placebo-controlled study

Q3 Medicine

Digital Chinese Medicine Pub Date : 2024-09-01 DOI:10.1016/j.dcmed.2024.12.002

S. Priyadharshini , A. Mooventhan , Venkatalakshmi Saravanan , N. Mangaiarkarasi

{"title":"Effects of needling at Sanyinjiao (SP6) acupuncture point on blood glucose levels and cardiovascular functions in patients with type 2 diabetes mellitus: a randomized placebo-controlled study","authors":"S. Priyadharshini , A. Mooventhan , Venkatalakshmi Saravanan , N. Mangaiarkarasi","doi":"10.1016/j.dcmed.2024.12.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To determine the effect of needling at Sanyinjiao (SP6) on random blood glucose (RBG) levels and cardiovascular function in patients with type 2 diabetes mellitus (T2DM).</div></div><div><h3>Methods</h3><div>In this randomized placebo-controlled study, T2DM patients (aged 35 – 65 years) were recruited from the Government Yoga and Naturopathy Medical College and Hospital, Chennai, India, between January 5, 2022 and March 15, 2023. Participants were randomly assigned to either acupuncture group or sham acupuncture group. The acupuncture group received bilateral needling at Sanyinjiao (SP6) while sham acupuncture group received needling at a non-acupuncture point [1.5 cun lateral to Sanyinjiao (SP6)] for 30 min. Primary outcome was RBG, and secondary outcomes included systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse rate (PR), pulse pressure (PP), mean arterial pressure (MAP), rate pressure product (RPP), and double product (Do-P). All parameters were assessed immediately before and after intervention.</div></div><div><h3>Results</h3><div>A total of 100 patients with T2DM were enrolled in the study, and blinded to acupuncture group (<em>n</em> = 50) and sham acupuncture group (<em>n</em> = 50). Intergroup analysis showed that significant reductions in RBG (<em>P <</em> 0.001), SBP (<em>P</em> = 0.035), DBP (<em>P</em> = 0.008), and MAP (<em>P</em> = 0.009) were found in acupuncture group compared with sham acupuncture group. Within-group analysis showed significant reductions in RBG (<em>P</em> < 0.001), SBP (<em>P</em> < 0.001), DBP (<em>P</em> = 0.008), PP (<em>P</em> = 0.023), MAP (<em>P</em> < 0.001), RPP (<em>P</em> < 0.001), and Do-P (<em>P</em> = 0.002) in acupuncture group, whereas sham acupuncture group showed a significant decrease in PR (<em>P</em> = 0.023) only in the post-test assessment compared with pre-test assessment.</div></div><div><h3>Conclusion</h3><div>A period of 30 min of needling at the Sanyinjiao (SP6) acupuncture point reduces RBG and promotes cardiovascular function in patients with T2DM as compared with needling at non-acupuncture points. Sanyinjiao (SP6) acupuncture may offer an immediate, non-pharmacological intervention to strengthen glycemic control management and cardiovascular health in T2DM patients.</div></div>","PeriodicalId":33578,"journal":{"name":"Digital Chinese Medicine","volume":"7 3","pages":"Pages 224-230"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Digital Chinese Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2589377724000582","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

To determine the effect of needling at Sanyinjiao (SP6) on random blood glucose (RBG) levels and cardiovascular function in patients with type 2 diabetes mellitus (T2DM).

Methods

In this randomized placebo-controlled study, T2DM patients (aged 35 – 65 years) were recruited from the Government Yoga and Naturopathy Medical College and Hospital, Chennai, India, between January 5, 2022 and March 15, 2023. Participants were randomly assigned to either acupuncture group or sham acupuncture group. The acupuncture group received bilateral needling at Sanyinjiao (SP6) while sham acupuncture group received needling at a non-acupuncture point [1.5 cun lateral to Sanyinjiao (SP6)] for 30 min. Primary outcome was RBG, and secondary outcomes included systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse rate (PR), pulse pressure (PP), mean arterial pressure (MAP), rate pressure product (RPP), and double product (Do-P). All parameters were assessed immediately before and after intervention.

Results

A total of 100 patients with T2DM were enrolled in the study, and blinded to acupuncture group (n = 50) and sham acupuncture group (n = 50). Intergroup analysis showed that significant reductions in RBG (P < 0.001), SBP (P = 0.035), DBP (P = 0.008), and MAP (P = 0.009) were found in acupuncture group compared with sham acupuncture group. Within-group analysis showed significant reductions in RBG (P < 0.001), SBP (P < 0.001), DBP (P = 0.008), PP (P = 0.023), MAP (P < 0.001), RPP (P < 0.001), and Do-P (P = 0.002) in acupuncture group, whereas sham acupuncture group showed a significant decrease in PR (P = 0.023) only in the post-test assessment compared with pre-test assessment.

Conclusion

A period of 30 min of needling at the Sanyinjiao (SP6) acupuncture point reduces RBG and promotes cardiovascular function in patients with T2DM as compared with needling at non-acupuncture points. Sanyinjiao (SP6) acupuncture may offer an immediate, non-pharmacological intervention to strengthen glycemic control management and cardiovascular health in T2DM patients.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊