The impact of the COVID-19 pandemic on DKA severity in Black and White pediatric patients.

IF 1 4区医学 Q4 ENDOCRINOLOGY & METABOLISM

Journal of Pediatric Endocrinology & Metabolism Pub Date : 2025-02-06 Print Date: 2025-04-28 DOI:10.1515/jpem-2024-0526

Shrina Patel, Elyzabeth Amador, Jonathan M Fischell, Erin Bewley, Kaitlin Jeffries, Paula G Newton, Stefanie Zaner Fischell

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引用次数: 0

Abstract

Objectives: Diabetic ketoacidosis (DKA) is a complication of uncontrolled diabetes mellitus, with a known increase in severity and incidence during the COVID-19 pandemic. Our institution also observed a rise in pediatric DKA cases in our largely underserved patient population. We hypothesized that the impact would be more pronounced in Black patients due to prepandemic healthcare inequities.

Methods: To investigate this, we confirmed the increased number of severe DKA cases in our pediatric patients during the pandemic and then stratified data to compare laboratory values between Black and White patients. We analyzed patients with a DKA diagnosis admitted to our institution's pediatric intensive care unit (PICU) prior to the pandemic (March 2016 to December 2017) and during its peak (March 2020 to December 2021).

Results and conclusions: Our data demonstrated more cases of severe DKA overall during 2020-2021 and when compared to prepandemic years, a statistically significant increase in severity for Black, but not White patients.

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COVID-19大流行对黑人和白人儿科患者DKA严重程度的影响

目的：糖尿病酮症酸中毒（DKA）是糖尿病未控制的并发症，已知在COVID-19大流行期间严重程度和发病率增加。我们的机构还观察到，在我们大部分服务不足的患者群体中，儿科DKA病例有所上升。我们假设，由于大流行前的医疗不平等，这种影响在黑人患者中更为明显。方法：为了调查这一点，我们证实在大流行期间，我们的儿科患者中严重DKA病例的数量有所增加，然后对数据进行分层，比较黑人和白人患者的实验室值。我们分析了在大流行之前（2016年3月至2017年12月）和高峰期间（2020年3月至2021年12月）入住我院儿科重症监护病房（PICU）诊断为DKA的患者。结果和结论：我们的数据显示，在2020-2021年期间，总体上有更多的严重DKA病例，与大流行前的年份相比，黑人患者的严重程度在统计学上显着增加，但白人患者没有。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Pediatric Endocrinology & Metabolism 医学-内分泌学与代谢

CiteScore

2.70

自引率

7.10%

发文量

176

审稿时长

3-6 weeks

期刊介绍： The aim of the Journal of Pediatric Endocrinology and Metabolism (JPEM) is to diffuse speedily new medical information by publishing clinical investigations in pediatric endocrinology and basic research from all over the world. JPEM is the only international journal dedicated exclusively to endocrinology in the neonatal, pediatric and adolescent age groups. JPEM is a high-quality journal dedicated to pediatric endocrinology in its broadest sense, which is needed at this time of rapid expansion of the field of endocrinology. JPEM publishes Reviews, Original Research, Case Reports, Short Communications and Letters to the Editor (including comments on published papers),. JPEM publishes supplements of proceedings and abstracts of pediatric endocrinology and diabetes society meetings.