Age-related sensitivity deterioration evaluation of positron emission tomography utilizing cross-calibration factor measurement data.

IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Radiological Physics and Technology Pub Date : 2025-03-01 Epub Date: 2025-02-05 DOI:10.1007/s12194-025-00882-6
Asuka Kikuchi, Shoichi Watanuki, Hiroshi Watabe, Manabu Tashiro
{"title":"Age-related sensitivity deterioration evaluation of positron emission tomography utilizing cross-calibration factor measurement data.","authors":"Asuka Kikuchi, Shoichi Watanuki, Hiroshi Watabe, Manabu Tashiro","doi":"10.1007/s12194-025-00882-6","DOIUrl":null,"url":null,"abstract":"<p><p>Age-related deterioration in positron emission tomography (PET) systems can be monitored using cross-calibration scans for scanner calibration. This study aimed to evaluate changes in the sensitivity of a PET system over time using routinely collected cross-calibration factor (CCF) measurement data and NEMA sensitivity measurement data acquired at our facility. We used CCF measurement data acquired over eight years, from 2016 to 2023. The count rates were calculated from raw data. The NEMA sensitivity measurements were also performed in 2017 and 2024 to compare with the sensitivities obtained from the CCF measurements. The PET images were reconstructed using the CCF data. A region of interest (ROI) was placed at the center of the PET images and count rates from the PET images were obtained. The sensitivity changes in the CCF data showed a linear decrease in sensitivity over eight years, with a mean annual reduction rate of approximately 2.0%. A comparison of the NEMA sensitivity measurements indicated a decrease in sensitivity, with a 12% reduction over eight eight years. The sensitivity was higher at the center of the axial field of view than at the edges. The ROI data also showed a linear decrease in sensitivity. This is consistent with the CCF data. Additionally, the coefficient of variation increased towards the edge of the slice. By utilizing the CCF measurement data, we obtained age-related changes in the PET system, suggesting that the PET system used in our facility may experience an annual sensitivity deterioration of approximately 2.0%.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"268-274"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11876247/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiological Physics and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12194-025-00882-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/5 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

Abstract

Age-related deterioration in positron emission tomography (PET) systems can be monitored using cross-calibration scans for scanner calibration. This study aimed to evaluate changes in the sensitivity of a PET system over time using routinely collected cross-calibration factor (CCF) measurement data and NEMA sensitivity measurement data acquired at our facility. We used CCF measurement data acquired over eight years, from 2016 to 2023. The count rates were calculated from raw data. The NEMA sensitivity measurements were also performed in 2017 and 2024 to compare with the sensitivities obtained from the CCF measurements. The PET images were reconstructed using the CCF data. A region of interest (ROI) was placed at the center of the PET images and count rates from the PET images were obtained. The sensitivity changes in the CCF data showed a linear decrease in sensitivity over eight years, with a mean annual reduction rate of approximately 2.0%. A comparison of the NEMA sensitivity measurements indicated a decrease in sensitivity, with a 12% reduction over eight eight years. The sensitivity was higher at the center of the axial field of view than at the edges. The ROI data also showed a linear decrease in sensitivity. This is consistent with the CCF data. Additionally, the coefficient of variation increased towards the edge of the slice. By utilizing the CCF measurement data, we obtained age-related changes in the PET system, suggesting that the PET system used in our facility may experience an annual sensitivity deterioration of approximately 2.0%.

利用交叉校准因子测量数据评价正电子发射断层扫描年龄相关性灵敏度退化。
正电子发射断层扫描(PET)系统中与年龄相关的退化可以使用交叉校准扫描进行扫描仪校准。本研究旨在利用常规收集的交叉校准因子(CCF)测量数据和我们工厂获得的NEMA灵敏度测量数据,评估PET系统灵敏度随时间的变化。我们使用了从2016年到2023年的8年间获得的CCF测量数据。计数率是根据原始数据计算的。还在2017年和2024年进行了NEMA灵敏度测量,以与CCF测量获得的灵敏度进行比较。利用CCF数据重建PET图像。将感兴趣区域(ROI)置于PET图像的中心,得到PET图像的计数率。CCF数据的敏感性变化在8年内呈线性下降,平均年下降率约为2.0%。NEMA灵敏度测量的比较表明灵敏度下降,在8年的时间里降低了12%。轴向视场中心的灵敏度高于边缘。ROI数据也显示灵敏度呈线性下降。这与CCF数据一致。此外,变异系数向切片边缘增大。通过利用CCF测量数据,我们获得了PET系统与年龄相关的变化,表明我们设施中使用的PET系统可能会经历每年约2.0%的灵敏度下降。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Radiological Physics and Technology
Radiological Physics and Technology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
3.00
自引率
12.50%
发文量
40
期刊介绍: The purpose of the journal Radiological Physics and Technology is to provide a forum for sharing new knowledge related to research and development in radiological science and technology, including medical physics and radiological technology in diagnostic radiology, nuclear medicine, and radiation therapy among many other radiological disciplines, as well as to contribute to progress and improvement in medical practice and patient health care.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信