Recent advances in the development of invasive ventilator liberation

Abstract

Invasive ventilation is a critical respiratory support technology in the intensive care unit (ICU). Increasing evidence suggests that early liberation from invasive ventilation can benefit patients. However, further research is needed to establish optimal criteria for invasive ventilator liberation programs, including the ideal screening frequency, appropriate techniques and duration of spontaneous breathing trials (SBT), evaluation of airway extubation readiness, and decision-making regarding extubation. The management of the invasive ventilator liberation process should encompass feasibility screening for SBTs, conducting SBTs, evaluating SBT outcomes, assessing airway extubation readiness, performing extubation itself, identifying high-risk factors associated with weaning failure, and developing clinical strategies. Additionally, a patient-centered assessment of the risks and consequences of extubation failure may serve as crucial measures to enhance the success rate of invasive ventilator liberation. Therefore, we conduct a detailed review of the related studies on invasive mechanical ventilation weaning to determine the best invasive ventilator liberation strategy.