{"title":"Heart rate variability may serve as an intermediate indicator for limiting atrial fibrillation in hypertensive patients","authors":"Hao Yang , Mi He , Yi He , Tao Liu , Houyuan Hu","doi":"10.1016/j.mehy.2024.111553","DOIUrl":null,"url":null,"abstract":"<div><div>Hypertension(HT) is a common disease and, if uncontrolled, may lead to atrial fibrillation (AF). Current research has revealed that the autonomic nervous system dysfunction (ANSD) and body fluid imbalance are important factors in the progression of HT. Hence, we hypothesize that by improving ANSD via intermittent monitoring of heart rate variability (HRV) in conjunction with effective blood-pressure control, anti-HT treatment may reduce AF events more successfully. This hypothesis presents a novel direction and perspective for further research into early interventions and ambulatory management for HT patients to limit the risk of AF.</div></div>","PeriodicalId":18425,"journal":{"name":"Medical hypotheses","volume":"195 ","pages":"Article 111553"},"PeriodicalIF":2.1000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical hypotheses","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0306987724002962","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Hypertension(HT) is a common disease and, if uncontrolled, may lead to atrial fibrillation (AF). Current research has revealed that the autonomic nervous system dysfunction (ANSD) and body fluid imbalance are important factors in the progression of HT. Hence, we hypothesize that by improving ANSD via intermittent monitoring of heart rate variability (HRV) in conjunction with effective blood-pressure control, anti-HT treatment may reduce AF events more successfully. This hypothesis presents a novel direction and perspective for further research into early interventions and ambulatory management for HT patients to limit the risk of AF.
期刊介绍:
Medical Hypotheses is a forum for ideas in medicine and related biomedical sciences. It will publish interesting and important theoretical papers that foster the diversity and debate upon which the scientific process thrives. The Aims and Scope of Medical Hypotheses are no different now from what was proposed by the founder of the journal, the late Dr David Horrobin. In his introduction to the first issue of the Journal, he asks ''what sorts of papers will be published in Medical Hypotheses? and goes on to answer ''Medical Hypotheses will publish papers which describe theories, ideas which have a great deal of observational support and some hypotheses where experimental support is yet fragmentary''. (Horrobin DF, 1975 Ideas in Biomedical Science: Reasons for the foundation of Medical Hypotheses. Medical Hypotheses Volume 1, Issue 1, January-February 1975, Pages 1-2.). Medical Hypotheses was therefore launched, and still exists today, to give novel, radical new ideas and speculations in medicine open-minded consideration, opening the field to radical hypotheses which would be rejected by most conventional journals. Papers in Medical Hypotheses take a standard scientific form in terms of style, structure and referencing. The journal therefore constitutes a bridge between cutting-edge theory and the mainstream of medical and scientific communication, which ideas must eventually enter if they are to be critiqued and tested against observations.