25 años de cirugía de Ross: seguimiento y resultados en pacientes reoperados en nuestro centro

IF 0.3 Q4 SURGERY
Consuelo M. Sisinni-Ganly, Julio C. Lugo-Adán, Francisco Estévez-Cid, Rocío Casais-Pampín, Juan J. Legarra-Calderón
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引用次数: 0

Abstract

Background

Ross surgery is a relatively infrequent procedure due to its technical complexity and its long-term outcomes not being exempt from controversy. We analyzed the outcomes of our series of patients undergoing the Ross procedure and those who required reintervention due to dysfunction of the pulmonary autograft or homograft.

Methods

Since 1998, 108 patients underwent Ross surgery at our center, with root replacement (RR) surgical technique used in 105 of them. We retrospectively reviewed data from a subgroup of patients who underwent reintervention after Ross surgery due to dysfunction of the autograft or homograft. Their characteristics and survival were studied using Kaplan-Meier analysis.

Results

The mean follow-up of the patients undergoing RR was 17.5 ± 5 years (median 19 years, range 0-25 years). During this period, 29 patients (26.9%) required at least one reintervention: 13 patients (44.8%) due to autograft dysfunction, 7 patients (24.1%) due to homograft dysfunction, and 9 patients (31%) due to dysfunction of both autograft and homograft. The mean time to reintervention due to autograft dysfunction was 11.8 ± 5.2 years (median 12 years, range 2-19 years) and due to homograft dysfunction was 12.6 ± 5 years (median 13 years, range 2-19 years). Hospital mortality was null. The follow-up of these reintervened patients was 18.7 ± 3.1 years (median 19 years, range 9-23), and the mortality during this period was 10% (n = 3): two due to cardiac causes and one due to non-cardiac causes. The cumulative survival function of patients who underwent reintervention at 10 years was 100%, and at 20 years it was 93%.

Conclusions

The Ross procedure is associated with a non-negligible risk of reoperation. In our series of patients, no early mortality has been observed following reoperation due to dysfunction of the pulmonary autograft or homograft.
Ross手术25年:在我们中心对再手术患者的跟踪和结果
背景:由于其技术复杂性和长期预后的争议,手术是一种相对少见的手术。我们分析了接受Ross手术的患者和由于自体或同种肺移植物功能障碍而需要再次干预的患者的结果。方法自1998年以来,108例患者在我中心行罗斯手术,其中105例采用根置换(RR)手术技术。我们回顾性地回顾了一组因自体移植物或同种移植物功能障碍而在Ross手术后进行再干预的患者的数据。采用Kaplan-Meier分析研究其特征和生存率。结果接受RR治疗的患者平均随访时间为17.5±5年(中位19年,0 ~ 25年)。在此期间,29例患者(26.9%)需要至少一次再干预:13例患者(44.8%)由于自体移植物功能障碍,7例患者(24.1%)由于同种移植物功能障碍,9例患者(31%)由于自体移植物和同种移植物功能障碍。自体移植物功能障碍导致再干预的平均时间为11.8±5.2年(中位12年,范围2-19年),同种移植物功能障碍导致再干预的平均时间为12.6±5年(中位13年,范围2-19年)。医院死亡率为零。这些再干预患者的随访时间为18.7±3.1年(中位19年,范围9-23年),期间死亡率为10% (n = 3):心脏原因2例,非心脏原因1例。10年再干预患者的累积生存功能为100%,20年为93%。结论Ross手术有不可忽视的再手术风险。在我们的患者系列中,没有观察到由于自体或同种肺移植物功能障碍而再次手术后的早期死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.50
自引率
66.70%
发文量
109
审稿时长
69 days
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