Luminescent Pentacene-Loaded Carbon Nanodots with Red-Light Triggered Photothermal and Photosensitizing Properties

IF 3 4区化学 Q3 CHEMISTRY, PHYSICAL

ChemPhotoChem Pub Date : 2024-10-08 DOI:10.1002/cptc.202400167

Giuseppe Forte, Grazia M. L. Consoli, Loredana Ferreri, Ludovica Maugeri, Alice Foti, Cristina Satriano, Giorgia Fangano, Salvatore Petralia

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Abstract

The development of multifunctional nanosystems for photo-induced hyperthermia and photodynamic effect is a challenging topic in the research of advanced materials for application in biomedical field. Here, we report red-luminescent carbon-nanodots (CDs-PNM/PTC) derived from entrapment of pentacene (PTC) in nanodots prepared from poly(N-isopropylacrylamide) polymer (CDs-PNM) by an easy and reagent-free method. The CD-PNM/PTC nanosystem was characterized by different techniques (UV-Vis spectrophotometry, fluorescence, NMR, AFM). Molecular modelling investigations were performed to unveil stability, structures and energy of the CD-PNM/PTC supramolecular adducts at 298 K and 315 K. The nanosized CDs-PNM/PTC exhibited excellent water-dispersibility, good photothermal conversion efficiency and photosensitizing effect at 680 nm. No significant toxicity and eukaryotic cell uptake are features that open to potential applications in photothermal-photodynamic treatments.

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来源期刊

ChemPhotoChem Chemistry-Physical and Theoretical Chemistry

CiteScore

5.80

自引率

5.40%

发文量

165

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