Physical Activity Reduces the Incidence of Sarcopenia in Middle-Aged Adults

IF 1 Q4 GERONTOLOGY

Ageing International Pub Date : 2025-02-04 DOI:10.1007/s12126-025-09590-3

Jin Luo, Raymond Y. W. Lee

{"title":"Physical Activity Reduces the Incidence of Sarcopenia in Middle-Aged Adults","authors":"Jin Luo, Raymond Y. W. Lee","doi":"10.1007/s12126-025-09590-3","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose of the Research</h3><p>The aim of this study was to investigate associations between physical activity and risk of sarcopenia in middle-aged adults.</p><h3>Methods</h3><p>This was a longitudinal study based on a subset of UK Biobank data consisting of 1,918 participants (902 men and 1,016 women, mean age 56 years) who had no sarcopenia at baseline based on the criteria of European Working Group on Sarcopenia in Older People (EWGSOP2). The participants were assessed again after 6 years at follow-up, and were categorized into no sarcopenia, probable sarcopenia, or sarcopenia using EWGSOP2. Physical activity was assessed at baseline using 7-day acceleration data that were analysed to obtain physical activity dose at different intensities. Multinominal logistic regression was employed to examine the association between the incidence of sarcopenia and physical activity dose, between baseline and follow up, controlled for other factors at baseline including age, sex, BMI, smoking status, intake of alcohol, vitamin D and calcium, history of rheumatoid arthritis, osteoarthritis, secondary osteoporosis, and type 2 diabetes.</p><h3>Results</h3><p>Among the 1918 participants with no sarcopenia at baseline, 230 (69 men and 161 women) developed probable sarcopenia and 37 (14 men and 23 women) developed sarcopenia at follow-up. Logistic regression models showed that increase in physical activity dose at moderate-to-vigorous intensity significantly reduced the risk of sarcopenia (odds ratio=0.368, <i>p</i><0.05), but not probable sarcopenia (odds ratio=0.974, <i>p</i>>0.05), while physical activity dose at light or very light activity intensity were not associated with the risk of sarcopenia or probable sarcopenia (<i>p</i>>0.05).</p><h3>Conclusions</h3><p>Physical activity at moderate-to-vigorous intensity could reduce risk of sarcopenia in middle-aged adults.</p></div>","PeriodicalId":51665,"journal":{"name":"Ageing International","volume":"50 1","pages":""},"PeriodicalIF":1.0000,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s12126-025-09590-3.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ageing International","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1007/s12126-025-09590-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"GERONTOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of the Research

The aim of this study was to investigate associations between physical activity and risk of sarcopenia in middle-aged adults.

Methods

This was a longitudinal study based on a subset of UK Biobank data consisting of 1,918 participants (902 men and 1,016 women, mean age 56 years) who had no sarcopenia at baseline based on the criteria of European Working Group on Sarcopenia in Older People (EWGSOP2). The participants were assessed again after 6 years at follow-up, and were categorized into no sarcopenia, probable sarcopenia, or sarcopenia using EWGSOP2. Physical activity was assessed at baseline using 7-day acceleration data that were analysed to obtain physical activity dose at different intensities. Multinominal logistic regression was employed to examine the association between the incidence of sarcopenia and physical activity dose, between baseline and follow up, controlled for other factors at baseline including age, sex, BMI, smoking status, intake of alcohol, vitamin D and calcium, history of rheumatoid arthritis, osteoarthritis, secondary osteoporosis, and type 2 diabetes.

Results

Among the 1918 participants with no sarcopenia at baseline, 230 (69 men and 161 women) developed probable sarcopenia and 37 (14 men and 23 women) developed sarcopenia at follow-up. Logistic regression models showed that increase in physical activity dose at moderate-to-vigorous intensity significantly reduced the risk of sarcopenia (odds ratio=0.368, p<0.05), but not probable sarcopenia (odds ratio=0.974, p>0.05), while physical activity dose at light or very light activity intensity were not associated with the risk of sarcopenia or probable sarcopenia (p>0.05).

Conclusions

Physical activity at moderate-to-vigorous intensity could reduce risk of sarcopenia in middle-aged adults.

查看原文本刊更多论文

体育锻炼可减少中年人肌肉减少症的发病率

研究目的本研究的目的是调查中年人体力活动与肌肉减少症风险之间的关系。方法：这是一项基于英国生物银行数据子集的纵向研究，该数据包括1,918名参与者（902名男性和1,016名女性，平均年龄56岁），根据欧洲老年人肌肉减少症工作组（EWGSOP2）的标准，基线时没有肌肉减少症。随访6年后再次对参与者进行评估，并使用EWGSOP2将其分为无肌少症、可能肌少症和肌少症。使用7天加速数据在基线时评估身体活动，分析这些数据以获得不同强度的身体活动剂量。采用多项logistic回归检验骨骼肌减少症发病率与体力活动剂量、基线与随访之间的关系，并控制基线时的其他因素，包括年龄、性别、BMI、吸烟状况、酒精、维生素D和钙的摄入、类风湿关节炎、骨关节炎、继发性骨质疏松症和2型糖尿病史。结果在1918名基线时没有肌肉减少症的参与者中，230名（69名男性和161名女性）出现了可能的肌肉减少症，37名（14名男性和23名女性）在随访时出现了肌肉减少症。Logistic回归模型显示，增加中等至剧烈运动强度的体力活动剂量可显著降低肌肉减少症的风险（优势比=0.368,p>0.05），但不能显著降低可能的肌肉减少症的风险（优势比=0.974,p>0.05），而轻度或极轻度运动强度的体力活动剂量与肌肉减少症或可能的肌肉减少症的风险无关（p>0.05）。结论中高强度体育锻炼可降低中年人肌肉减少症的发生风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Ageing International GERONTOLOGY-

CiteScore

2.70

自引率

6.70%

发文量

期刊介绍： As a quarterly peer-reviewed journal that has existed for over three decades, Ageing International serves all professionals who deal with complex ageing issues. The journal is dedicated to improving the life of ageing populations worldwide through providing an intellectual forum for communicating common concerns, exchanging analyses and discoveries in scientific research, crystallizing significant issues, and offering recommendations in ageing-related service delivery and policy making. Besides encouraging the submission of high-quality research and review papers, Ageing International seeks to bring together researchers, policy analysts, and service program administrators who are committed to reducing the ''implementation gap'' between good science and effective service, between evidence-based protocol and culturally suitable programs, and between unique innovative solutions and generalizable policies. For significant issues that are common across countries, Ageing International will organize special forums for scholars and investigators from different disciplines to present their regional perspectives as well as to provide more comprehensive analysis. The editors strongly believe that such discourse has the potential to foster a wide range of coordinated efforts that will lead to improvements in the quality of life of older persons worldwide. Abstracted and Indexed in: ABI/INFORM, Academic OneFile, Academic Search, CSA/Proquest, Current Abstracts, EBSCO, Ergonomics Abstracts, Expanded Academic, Gale, Google Scholar, Health Reference Center Academic, OCLC, PsychINFO, PsyARTICLES, SCOPUS, Social Science Abstracts, and Summon by Serial Solutions.