P-75 INFLUENCE OF THE ARTERIAL HEPATIC FLOW IN ELASTOGRAPHY (2D SHEARWAVE) LIVER VALUES

Abstract

Conflict of interest

No

Introduction and Objectives

The liver receives blood at low pressure through the portal vein (80%). Distortion of hepatic histoarchitecture, reduces portal flow and increases hepatic arterial flow (HAF). Liver elastography (LE) non-invasively measures liver stiffness (LS), but intrahepatic and extrahepatic factors also influence LS. The velocity-time integral of the hepatic artery (HAVTI) estimates the area under the spectral Doppler curve. This study investigates the correlation between LS and HAVTI in cirrhosis patients, aiming to explain dynamic LS changes in cirrhosis and portal hypertension.

Patients / Materials and Methods

Elastography and spleno-portal Doppler were performed on cirrhosis patients under follow-up at Sanatorio Sagrado Corazón. The median of five LS measurements was determined, and the HAVTI was measured in the same study. Spearman's correlation method was used to establish the correlation between LE values and HAVTI

Results and Discussion

Twenty cirrhosis patients were evaluated (65% men), with a median age of 58 years. The most common etiology was HCV (35%), followed by alcohol use disorders (30%). Seventy percent were CHILD A (median MELD-Na 10). At the time of the study, 68.4% had experienced at least one decompensation event. We found a correlation of r = 0.65 (p = 0.004) between hepatic elastography values and HAVTI.

Conclusions

Our study demonstrates a significant correlation between LS and HAVTI in cirrhosis patients. This suggests that non-invasive HAVTI assessment may provide valuable insights into dynamic LS changes associated with cirrhosis and portal hypertension.