Dynamics of diabetes prevalence, incidence and mortality in France: A nationwide study, 2013–2021

IF 4.6 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes & metabolism Pub Date : 2025-01-31 DOI:10.1016/j.diabet.2025.101615

Sandrine Fosse-Edorh , Marie Guion , Sarah Goria , Laurence Mandereau-Bruno , Emmanuel Cosson

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引用次数: 0

Abstract

Aim

To estimate the time trends of treated diabetes incidence, prevalence and mortality in France from 2013 to 2019 and to compare with the Covid-19 pandemic period (2020–2021).

Methods

Using the French National Health Data System, people with treated diabetes ≥ 45 years-old were identified based on their medications. Annual time trends over 2013–2019 were estimated using Poisson log-linear model controlled for age, year and region for prevalence (aPTT), incidence (aITT) and mortality (aMTT). Numbers of incident cases and deaths in 2020–2021 were estimated from these trends, and compared with those observed.

Results

Over 2013–2019, incidence and mortality declined significantly in men, aITT=-0.61 % (-0.95;-0.26); aMTT=-0.52 % (-0.81;-0.22), leading to a stable prevalence, aPTT=0.18 % (-0.03;0.40). In women, the fall in incidence was more marked, aITT=-1.45 % (-1.95;-0.95), mortality was stable, aMTT=-0.19 % (-0.54;0.15), leading to a significant decrease in prevalence, aPTT=-0.31 % (-0.60;-0.02). Compared with people not treated for diabetes, the relative risk of mortality increased significantly in men over the 2013–2019 period, from 1.38 (1.37;1.39) to 1.42 (1.41;1.43), while the risk remained stable in women, from 1.45 (1.44;1.46) to 1.46 (1.45;1.47).

In 2020, there were 7,458 and 4,404 additional deaths and 3,550 and 4,919 new cases in respectively men and women. In 2021, there were 11,576 and 6,371 additional deaths and 30,057 and 26,169 new cases in respectively men and women.

Conclusion

This study reports a favorable dynamic of diabetes over 2013–2019 followed by a sharp increase in incidence and mortality in 2020 and 2021. Continued monitoring is necessary to identify long-term trend and potential indirect effect of the pandemic.

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2013-2021年法国糖尿病患病率、发病率和死亡率动态研究

目的：估计2013 - 2019年法国治疗糖尿病发病率、患病率和死亡率的时间趋势，并与2019冠状病毒病大流行期（2020-2021年）进行比较。方法：使用法国国家健康数据系统，根据用药情况确定≥45岁的糖尿病患者。使用泊松对数线性模型对2013-2019年的年度时间趋势进行了估计，该模型控制了年龄、年份和地区的患病率（aPTT）、发病率（aITT）和死亡率（aMTT）。根据这些趋势估计了2020-2021年的事件病例数和死亡人数，并与观察到的情况进行了比较。结果：2013-2019年，男性的发病率和死亡率显著下降，aITT=-0.61% (-0.95;-0.26)；aMTT=-0.52%(-0.81;-0.22)，患病率稳定，aPTT=0.18%（-0.03;0.40）。在女性中，发病率下降更为明显，aITT=-1.45%(-1.95;-0.95)，死亡率稳定，aMTT=-0.19%(-0.54;0.15)，导致患病率显著下降，aPTT=-0.31%（-0.60;-0.02）。与未接受糖尿病治疗的人相比，2013-2019年期间，男性的相对死亡风险显著增加，从1.38（1.37;1.39）增加到1.42(1.41;1.43)，而女性的风险保持稳定，从1.45（1.44;1.46）增加到1.46（1.45;1.47）。2020年，男性和女性分别新增死亡7 458人和4 404人，新增病例3 550人和4 919人。2021年，男性和女性的死亡人数分别增加了11 576人和6 371人，新增病例分别为300 057人和26 169人。结论：本研究报告了2013-2019年糖尿病的有利动态，随后在2020年和2021年发病率和死亡率急剧上升。有必要继续进行监测，以确定大流行的长期趋势和潜在的间接影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes & metabolism 医学-内分泌学与代谢

CiteScore

12.00

自引率

4.20%

发文量

审稿时长

13 days

期刊介绍： A high quality scientific journal with an international readership Official publication of the SFD, Diabetes & Metabolism, publishes high-quality papers by leading teams, forming a close link between hospital and research units. Diabetes & Metabolism is published in English language and is indexed in all major databases with its impact factor constantly progressing. Diabetes & Metabolism contains original articles, short reports and comprehensive reviews.