Estimation of dose to a bystander from F-18 FDG patients using Monte Carlo simulation in clinical exposure scenarios.

IF 2.4 4区 医学 Q3 ENGINEERING, BIOMEDICAL
K W N S Samaranayake, Erin Mckay, Thomas Hennessy
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Abstract

The radiation exposure to bystanders from nuclear medicine patients is a common concern raised in nuclear medicine departments. The GATE (Geant4 Application for Tomographic Emission) Monte Carlo radiation transport application was used to estimate the dose to a bystander. Two voxelised phantoms were utilised in a GATE Monte Carlo simulation as the radiation source and target. The absorbed dose to the target phantom from radiation emitted by the source phantom was calculated. Three experimental setups of increasing complexity, with the last one replicating clinical dose rate measurements, were used to validate the simulation results. Four clinical scenarios were simulated to estimate the dose to a healthcare worker from F-18 FDG patients: an ultrasound procedure, two surgical procedures (head and chest), and a face-to-face consultation. The mean absorbed dose to the foetus was also estimated using the same method and pregnant female phantoms as target for ultrasound scan scenario. The effective dose to a healthcare worker from an FDG PET patient who has had 250 MBq of FDG injection 3 h post procedures was estimated as: 18.1 ± 0.1 µSv for 30-minute ultrasound scan, 36.5 ± 0.3 µSv for 1-hour chest surgical procedure, and 9.3 ± 0.1 µSv for 15-minute face to face consultation scenario. This method can be easily extended to estimate the dose to bystanders from nuclear medicine patients injected with various radioisotopes in different clinical scenarios.

使用蒙特卡罗模拟在临床暴露情景中估计F-18 FDG患者对旁观者的剂量
核医学患者对旁观者的辐射暴露是核医学部门普遍关注的问题。使用GATE (Geant4应用程序层析发射)蒙特卡罗辐射传输应用程序来估计对旁观者的剂量。在GATE蒙特卡罗模拟中,两个体素幻影分别作为辐射源和目标。计算了源幻体辐射对目标幻体的吸收剂量。使用三个越来越复杂的实验装置,最后一个复制临床剂量率测量,来验证模拟结果。模拟了四种临床情景,以估计F-18 FDG患者对医护人员的剂量:一次超声检查、两次外科手术(头部和胸部)和一次面对面咨询。用同样的方法估计胎儿的平均吸收剂量,并以孕妇幻影为超声扫描情景的目标。一名FDG PET患者在手术后3小时注射了250 MBq的FDG,对医护人员的有效剂量估计为:超声扫描30分钟18.1±0.1µSv,胸部手术1小时36.5±0.3µSv,面对面咨询15分钟9.3±0.1µSv。该方法可以很容易地推广到估计核医学患者在不同临床情况下注射各种放射性同位素对旁观者的剂量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.40
自引率
4.50%
发文量
110
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