Health-related quality of life and mental health outcomes among cancer survivors in an insomnia intervention: a randomized controlled trial.

IF 3.6 2区心理学 Q1 PSYCHOLOGY, MULTIDISCIPLINARY

Annals of Behavioral Medicine Pub Date : 2025-01-04 DOI:10.1093/abm/kaae096

Misol Kwon, Jingtao Zhu, Gregory E Wilding, Karen Larkin, Philip R Gehrman, Suzanne S Dickerson

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引用次数: 0

Abstract

Background: While brief behavioral therapy for insomnia (BBTI) has shown promising results in improving sleep outcomes, its effects on health-related quality of life (HRQOL) and mental health among cancer survivors have been understudied.

Purpose: To evaluate the effect of BBTI on HRQOL and mental health outcomes among cancer survivors, relative to an attention control group receiving a healthy eating program (HEP), over periods from baseline to 12 months and from 3 to 12 months.

Methods: A sample of 132 cancer survivors with insomnia symptoms (Mage: 63.7 ± 10 years; 55.3% female) was assessed at baseline, with the final analytical sample of 121 (BBTI = 62, HEP = 59). Self-reported HRQOL, mood disturbance, depression, and anxiety at baseline, 3 months, and 12 months were examined. A multivariate linear model using least squares means evaluated within- and between-group differences.

Results: No significant differences in outcome variables were found between the randomized groups at any time point. Both groups showed significant improvements in total HRQOL, mood disturbance, and anxiety symptoms from baseline to 12 months. Only the BBTI group demonstrated a significant reduction in depressive symptoms within the group, an effect not observed in the HEP group. The most noticeable changes occurred within the first 3 months, with no statistically significant differences from 3 to 12 months within or between groups.

Conclusion: While both randomized groups showed improvements in total HRQOL, mood, and anxiety symptoms, only BBTI produced significant within-group improvements in depressive symptoms over 12 months.

Clinical trial registration: https://ClinicalTrials.gov, NCT03810365.

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失眠干预中癌症幸存者的健康相关生活质量和心理健康结果：一项随机对照试验

背景：虽然失眠的短暂行为疗法（BBTI）在改善睡眠结果方面显示出有希望的结果，但其对癌症幸存者健康相关生活质量（HRQOL）和心理健康的影响尚未得到充分研究。目的：评估BBTI对癌症幸存者的HRQOL和心理健康结果的影响，相对于接受健康饮食计划（HEP）的注意对照组，从基线到12个月和从3到12个月。方法：选取132例有失眠症状的癌症幸存者(年龄：63.7±10岁；55.3%女性)在基线时进行评估，最终分析样本为121例（BBTI = 62, HEP = 59）。在基线、3个月和12个月检查自我报告的HRQOL、情绪障碍、抑郁和焦虑。使用最小二乘的多元线性模型评估组内和组间差异。结果：在任意时间点，随机分组间的结局变量均无显著差异。从基线到12个月，两组在总体HRQOL、情绪障碍和焦虑症状方面均有显著改善。只有BBTI组在组内表现出抑郁症状的显著减少，HEP组没有观察到这种效果。最明显的变化发生在前3个月内，组内或组间3至12个月无统计学差异。结论：虽然两个随机组在总体HRQOL、情绪和焦虑症状方面都有改善，但只有BBTI在12个月内显著改善了组内抑郁症状。临床试验注册：https://ClinicalTrials.gov, NCT03810365。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Behavioral Medicine PSYCHOLOGY, MULTIDISCIPLINARY-

CiteScore

7.00

自引率

5.30%

发文量

期刊介绍： Annals of Behavioral Medicine aims to foster the exchange of knowledge derived from the disciplines involved in the field of behavioral medicine, and the integration of biological, psychosocial, and behavioral factors and principles as they relate to such areas as health promotion, disease prevention, risk factor modification, disease progression, adjustment and adaptation to physical disorders, and rehabilitation. To achieve these goals, much of the journal is devoted to the publication of original empirical articles including reports of randomized controlled trials, observational studies, or other basic and clinical investigations. Integrative reviews of the evidence for the application of behavioral interventions in health care will also be provided. .