PhysioEx, a new Python library for explainable sleep staging through deep learning.

IF 2.3 4区 医学 Q3 BIOPHYSICS
Guido Gagliardi, Luca Alfeo, Mario G C A Cimino, Gaetano Valenza, Maarten De Vos
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引用次数: 0

Abstract

Objective: Sleep staging is a crucial task in clinical and research contexts for diagnosing and understanding sleep disorders. This work introduces PhysioEx, a Python library designed to support the analysis of sleep stages using deep learning and Explainable AI (XAI). Approach: PhysioEx provides an extensible and modular API for standardizing and automating the sleep staging pipeline, covering data preprocessing, model training, testing, fine-tuning, and explainability. It supports both low-resource devices and high-performance computing clusters and includes pretrained models based on the Sleep Heart Health Study (SHHS) dataset. These models support single-channel EEG and multichannel EEG-EOG-EMG configurations and are easily adaptable to custom datasets. PhysioEx also features a command-line interface toolbox allowing users to streamline the model development and deployment. The library offers a range of XAI post-hoc methods to explain model decisions and align them with expert knowledge. Main results: PhysioEx benchmark state-of-the-art sleep staging models in a standard pipeline. Enabling a fair comparison between them both on the training source and out-of-domain sources. Its XAI techniques provide insights into deep learning-based sleep staging by linking model decisions to human-understandable concepts, such as AASM-defined rules. Significance: PhysioEx addresses the need for a standardized and accessible platform for sleep staging analysis, combining deep learning and XAI. By supporting modular workflows and explainable insights, it bridges the gap between machine learning models and clinical expertise. PhysioEx is publicly available and installable via pip, making it a valuable tool for researchers and practitioners in sleep medicine.

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来源期刊
Physiological measurement
Physiological measurement 生物-工程:生物医学
CiteScore
5.50
自引率
9.40%
发文量
124
审稿时长
3 months
期刊介绍: Physiological Measurement publishes papers about the quantitative assessment and visualization of physiological function in clinical research and practice, with an emphasis on the development of new methods of measurement and their validation. Papers are published on topics including: applied physiology in illness and health electrical bioimpedance, optical and acoustic measurement techniques advanced methods of time series and other data analysis biomedical and clinical engineering in-patient and ambulatory monitoring point-of-care technologies novel clinical measurements of cardiovascular, neurological, and musculoskeletal systems. measurements in molecular, cellular and organ physiology and electrophysiology physiological modeling and simulation novel biomedical sensors, instruments, devices and systems measurement standards and guidelines.
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