Nitroimidazoles in Albanian honey samples by LC-MS/MS analysis.

IF 2.5 3区农林科学 Q2 CHEMISTRY, APPLIED

Food additives & contaminants. Part B, Surveillance Pub Date : 2025-06-01 Epub Date: 2025-01-29 DOI:10.1080/19393210.2025.2457134

Ina Pasho, Kozeta Vaso, Landi Dardha

引用次数: 0

Abstract

This study employed QuEChERS extraction method combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) to analyse honey samples from Albania for nitroimidazole residues. This approach allowed for the detection of trace-level residues, achieving sensitivity in the parts per billion range. Out of the 45 honey samples analysed, 6 exceeded the European Union's safety limit of 1 µg/kg, with metronidazole (MNZ) and dimetridazole (DMZ) being the predominant contaminants. The findings highlight the public health risk posed by nitroimidazole residues, particularly in regions where honey is a widely consumed food product. In line with recent advances in the determination of veterinary drug residues, this study supports the need for enhanced regulatory frameworks and continuous monitoring to safeguard consumer health.

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LC-MS/MS分析阿尔巴尼亚蜂蜜样品中的硝基咪唑。

采用QuEChERS萃取-液相色谱-串联质谱（LC-MS/MS）联用技术对阿尔巴尼亚蜂蜜中硝基咪唑残留进行分析。这种方法允许检测痕量残留，达到十亿分之一范围内的灵敏度。在分析的45个蜂蜜样本中，有6个超过了欧盟的安全限值1微克/千克，其中甲硝唑（MNZ）和二甲硝唑（DMZ）是主要污染物。研究结果强调了硝基咪唑残留对公众健康造成的风险，特别是在蜂蜜被广泛食用的地区。根据兽药残留测定的最新进展，本研究支持加强监管框架和持续监测以保障消费者健康的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Food additives & contaminants. Part B, Surveillance 农林科学-毒理学

CiteScore

5.30

自引率

10.30%

发文量

审稿时长

2.7 months

期刊介绍： Food Additives & Contaminants: Part B publishes surveillance data indicating the presence and levels of occurrence of designated food additives, residues and contaminants in foods, food supplements and animal feed. Data using validated methods must meet stipulated quality standards to be acceptable and must be presented in a prescribed format for subsequent data-handling. Food Additives & Contaminants: Part B restricts its scope to include certain classes of food additives, residues and contaminants. This is based on a goal of covering those areas where there is a need to record surveillance data for the purposes of exposure and risk assessment. The scope is initially restricted to: Additives - food colours, artificial sweeteners, and preservatives; Residues – veterinary drug and pesticide residues; Contaminants – metals, mycotoxins, phycotoxins, plant toxins, nitrate/nitrite, PCDDs/PCFDs, PCBs, PAHs, acrylamide, 3-MPCD and contaminants derived from food packaging. Readership: The readership includes scientists involved in all aspects of food safety and quality and particularly those involved in monitoring human exposure to chemicals from the diet. Papers reporting surveillance data in areas other than the above should be submitted to Part A . The scope of Part B will be expanded from time-to-time to ensure inclusion of new areas of concern.