Measurement and spectral analysis of medical shock wave parameters based on flexible PVDF sensors.

IF 2.4 4区 医学 Q3 ENGINEERING, BIOMEDICAL
Liansheng Xu, Fei Shen, Fan Fan, Qiong Wu, Li Wang, Fengji Li, Yubo Fan, Haijun Niu
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Abstract

Extracorporeal shock wave therapy (ESWT) achieves its therapeutic purpose mainly through the biological effects produced by the interaction of shock waves with tissues, and the accurate measurement and calculation of the mechanical parameters of shock waves in tissues are of great significance in formulating the therapeutic strategy and evaluating the therapeutic effect. This study utilizes the approach of implanting flexible polyvinylidene fluoride (PVDF) vibration sensors inside the tissue-mimicking phantom of various thicknesses to capture waveforms at different depths during the impact process in real time. Parameters including positive and negative pressure changes (P+, P-), pulse wave rise time ([Formula: see text]), and energy flux density (EFD) are calculated, and frequency spectrum analysis of the waveforms is conducted. The dynamic response, propagation process, and attenuation law of the shock wave in the phantom under different impact intensities were analyzed. Results showed that flexible PVDF sensors could precisely acquire the characteristics of pulse waveform propagating within the phantom. At the same depth, as the driving pressure increases, P+ and P- increase linearly, and [Formula: see text] remains constant. At the same driving pressure, P+, P-, and EFD decay exponentially with increasing propagation depth. At the same depth, the spectra of pulse waveforms are similar, and the increasing driving pressure does not cause significant changes in carrier frequency and modulation frequency. The research findings could provide a reference for developing ESWT devices, improving treatment strategies, and enhancing the safety of clinical applications.

基于柔性PVDF传感器的医疗冲击波参数测量与光谱分析。
体外冲击波治疗(Extracorporeal shock wave therapy, ESWT)主要通过冲击波与组织相互作用产生的生物效应来达到治疗目的,准确测量和计算组织中冲击波的力学参数对制定治疗策略和评价治疗效果具有重要意义。本研究利用柔性聚偏氟乙烯(PVDF)振动传感器植入不同厚度的仿组织模体中,实时捕捉冲击过程中不同深度的波形。计算正、负压变化(P+、P-)、脉冲波上升时间([公式:见文])、能量通量密度(EFD)等参数,并对波形进行频谱分析。分析了不同冲击强度下冲击波在仿真体中的动态响应、传播过程和衰减规律。结果表明,柔性PVDF传感器可以准确地获取脉冲波形在体内传播的特性。在同一深度,随着驱动压力的增加,P+和P-线性增加,[公式:见文]保持不变。在相同的驱动压力下,P+、P-和EFD随传播深度的增加呈指数衰减。在相同深度下,脉冲波形的频谱相似,驱动压力的增加不会引起载频和调制频率的显著变化。研究结果可为开发ESWT装置、改进治疗策略、提高临床应用安全性提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.40
自引率
4.50%
发文量
110
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