The Premonitory Urge to Tic in Children and Adolescents: Measuring, Describing, and Correlating

IF 3.2 3区医学 Q2 CLINICAL NEUROLOGY

Pediatric neurology Pub Date : 2025-01-09 DOI:10.1016/j.pediatrneurol.2024.12.017

Liping Yu MM , Yanlin Li MM , Hanxue Yang PhD , Yonghua Cui PhD , Ying Li PhD

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Abstract

Background

This study aimed to explore the premonitory urges (PUs) experienced by children with tic disorders (TDs), with the aim of describing and correlating these urges with various factors.

Methods

First-episode and drug-naive patients with TDs were recruited. We conducted a comprehensive study utilizing the Premonitory Urge for Tics Scale to measure the severity of PUs. Regression analysis was performed to explore the relationships between PUs and other relevant factors, such as demographic characteristics, tic severity, and comorbidities.

Results

The linear regression model revealed that age (β = 0.090, P = 0.004), the severity of motor tics (β = 0.112, P < 0.001), the severity of vocal tics (β = 0.074, P = 0.020), and the severity of tic-related impairments (β = 0.112, P = 0.001) were significant predictors of PUs.

Conclusions

This study provides insights into the nature of PUs in children with TD. Future research should focus on PUs across different age groups and develop and evaluate targeted treatments that aim to reduce the severity of tics.

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来源期刊

Pediatric neurology 医学-临床神经学

CiteScore

4.80

自引率

2.60%

发文量

176

审稿时长

78 days

期刊介绍： Pediatric Neurology publishes timely peer-reviewed clinical and research articles covering all aspects of the developing nervous system. Pediatric Neurology features up-to-the-minute publication of the latest advances in the diagnosis, management, and treatment of pediatric neurologic disorders. The journal''s editor, E. Steve Roach, in conjunction with the team of Associate Editors, heads an internationally recognized editorial board, ensuring the most authoritative and extensive coverage of the field. Among the topics covered are: epilepsy, mitochondrial diseases, congenital malformations, chromosomopathies, peripheral neuropathies, perinatal and childhood stroke, cerebral palsy, as well as other diseases affecting the developing nervous system.