[Neurocognitive Performance in Patients with End-Stage Chronic Kidney Disease: Differences Between Conservative Medical Management and Hemodialysis].

Revista medica de Chile Pub Date : 2024-11-01 DOI:10.4067/s0034-98872024000800856

Luna Sánchez, Bárbara Lanis, Nicolás Meza, Gustav Rohde

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Abstract

No consensus has been reached about how cognitive performance evolves in patients receiving hemodialysis (HD).

Aim: to analyze the cognitive performance of patients with end-stage chronic kidney disease (CKD) undergoing conservative medical management or HD.

Methods: We conducted a cross-sectional study. The cognitive performance of both groups was assessed through the INECO Frontal Screening (IFS) instrument.

Results: 6 patients were analyzed in each group (n= 12). A significant difference was observed for the total IFS score, with 14.4±6.29 points in the HD group and 21.5±3.96 points in the conservative management group (p<0.05). Regarding the specific domains of the IFS, a significant difference was found in the domain of verbal inhibitory control, with an average of 1.83±1.17 points in the HD group and 4±0.89 points in the conservative management group (p<0.05). No associations were elucidated on the abbreviated MMSE, ACE-III, TMT-A and B, Grober and Buschke Test, Stroop Test and Boston Test Nomination Test.

Conclusion: Patients with terminal CKD on HD (even those with a normal MMSE result) show an impairment in their executive functions compared to those who underwent conservative management.

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[终末期慢性肾病患者的神经认知表现：保守治疗与血液透析的差异]。

关于接受血液透析（HD）的患者的认知表现如何演变尚未达成共识。目的：分析终末期慢性肾脏疾病（CKD）保守治疗或HD患者的认知能力。方法：我们进行了横断面研究。两组患者的认知能力均通过INECO额叶筛查（IFS）量表进行评估。结果：每组分析6例患者（n= 12）。在IFS总分上观察到显著差异，HD组为14.4±6.29分，保守治疗组为21.5±3.96分(p结论：终末期CKD患者（即使MMSE结果正常）与接受保守治疗的患者相比，其执行功能受损。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Revista medica de Chile

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