The Critical Management of Spinal Cord Injury: A Narrative Review.

IF 1.7 Q2 MEDICINE, GENERAL & INTERNAL
Emilio Moreno-González, Antonio Ibarra
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引用次数: 0

Abstract

Spinal cord injury (SCI) is defined as physical damage that alters the function and structure of the spinal cord. Traumatic causes, such as vehicle accidents, falls, and violence, account for 90% of SCI cases. Recent evidence suggests that early intensive care unit (ICU) monitoring improves patient prognosis, highlighting the importance of prompt ICU admission and early decompression surgery. This review includes 50 publications selected based on specific criteria to gather evidence on the current management of SCI in acute settings. Pharmacological agents have been studied for their neuroprotective properties, offering hope for improved neurological outcomes. Several clinical trials are evaluating new pharmacological alternatives for SCI. In conclusion, the current management of acute SCI should focus on standardized treatments addressing ventilatory, cardiopulmonary, and hematologic complications, all of which directly impact long-term neurological and functional prognosis. New neuroprotective agents currently in clinical trials show promising results and should be further studied to determine their role in acute SCI management.

脊髓损伤的关键管理:叙述回顾。
脊髓损伤(SCI)被定义为改变脊髓功能和结构的物理损伤。创伤性原因,如车祸、跌倒和暴力,占脊髓损伤病例的90%。最近的证据表明,早期重症监护病房(ICU)监测可改善患者预后,强调了及时进入ICU和早期减压手术的重要性。本综述包括50篇基于特定标准的出版物,以收集当前急性脊髓损伤管理的证据。药理药物已被研究其神经保护特性,为改善神经预后提供了希望。一些临床试验正在评估新的SCI药物替代品。总之,目前急性脊髓损伤的管理应侧重于解决通气、心肺和血液学并发症的标准化治疗,所有这些并发症都直接影响长期神经和功能预后。目前正在临床试验中的新型神经保护剂显示出良好的效果,需要进一步研究以确定其在急性脊髓损伤治疗中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinics and Practice
Clinics and Practice MEDICINE, GENERAL & INTERNAL-
CiteScore
2.60
自引率
4.30%
发文量
91
审稿时长
10 weeks
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