Delayed Surgery Increases the Rate of Infection in Closed Diaphyseal Tibial and Femoral Fractures.

IF 4.4 1区 医学 Q1 ORTHOPEDICS
Aditya Subramanian, Francisco Gomez-Alvarado, Jamieson O'Marr, Michael Flores, Babapelumi Adejuyigbe, Syed Ali, Patricia Rodarte, Hannah Elsevier, Abigail Cortez, Mayur Urva, Saam Morshed, David Shearer
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Abstract

Background: Although delays in musculoskeletal care in low- and middle-income countries (LMICs) are well documented in the open fracture literature, the impact of surgical delays on closed fractures is not well understood. This study aimed to assess the impact of surgical delay on the risk of infection in closed long-bone fractures treated with intramedullary nailing in LMICs.

Methods: Using the SIGN (Surgical Implant Generation Network) Surgical Database, patients ≥16 years of age who were treated with intramedullary nailing for closed diaphyseal femoral and tibial fractures from January 2018 to December 2021 were identified. Infection was diagnosed based on the assessment by the treating surgeon. A logistic regression model, adjusting for potential confounders, was used to analyze the association between delays to surgery (in weeks) and infection.

Results: Of the 9,477 closed fractures that were included in this study, 58% were femoral fractures and 42% were tibial fractures. The mean age was 35 years, and 76.2% of the patients were men. The mean delay to surgery was 10.5 days, and the median delay to surgery was 6 days. The overall infection rate was 3.1%. The odds of developing an infection increased by 9.2% with each week of delayed surgical treatment (odds ratio,1.092; 95% confidence interval, 1.042 to 1.145). Increasing delays were also associated with longer surgery duration and higher rates of open reduction.

Conclusions: Surgical delays in LMICs were associated with an increased risk of infection in closed long-bone fractures. This study quantified the increased risk of infection due to delays in receiving care, highlighting the importance of timely surgery for closed fractures in LMICs.

Level of evidence: Therapeutic Level III . See Instructions for Authors for a complete description of levels of evidence.

延迟手术增加闭合性胫骨和股骨干骨折的感染率。
背景:尽管在低收入和中等收入国家(LMICs)的开放性骨折文献中有很好的记录,但手术延迟对闭合性骨折的影响尚不清楚。本研究旨在评估手术延迟对中低收入患者髓内钉治疗闭合性长骨骨折感染风险的影响。方法:使用SIGN(外科植入物生成网络)手术数据库,识别2018年1月至2021年12月期间接受髓内钉治疗闭合性股骨骨干和胫骨骨折的患者,年龄≥16岁。根据治疗外科医生的评估诊断感染。使用逻辑回归模型,调整潜在的混杂因素,分析手术延迟(以周为单位)与感染之间的关系。结果:在本研究纳入的9,477例闭合性骨折中,58%为股骨骨折,42%为胫骨骨折。平均年龄35岁,男性占76.2%。平均手术延迟为10.5天,中位手术延迟为6天。总感染率为3.1%。每延迟一周的手术治疗,发生感染的几率增加9.2%(优势比,1.092;95%置信区间为1.042 ~ 1.145)。延迟时间的增加也与手术时间的延长和切开复位率的提高有关。结论:手术延迟与闭合性长骨骨折感染风险增加有关。本研究量化了因接受治疗延误而增加的感染风险,强调了中低收入患者闭合性骨折及时手术的重要性。证据等级:治疗性III级。有关证据水平的完整描述,请参见作者说明。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.90
自引率
7.50%
发文量
660
审稿时长
1 months
期刊介绍: The Journal of Bone & Joint Surgery (JBJS) has been the most valued source of information for orthopaedic surgeons and researchers for over 125 years and is the gold standard in peer-reviewed scientific information in the field. A core journal and essential reading for general as well as specialist orthopaedic surgeons worldwide, The Journal publishes evidence-based research to enhance the quality of care for orthopaedic patients. Standards of excellence and high quality are maintained in everything we do, from the science of the content published to the customer service we provide. JBJS is an independent, non-profit journal.
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