Response to functional restoration in non-specific chronic low back pain with Modic type 1 changes.

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
European Spine Journal Pub Date : 2025-03-01 Epub Date: 2025-01-24 DOI:10.1007/s00586-025-08665-8
Louis Jacob, Agathe Clouzeau, Agnès Ostertag, David Petrover, Jean-François Vergnol, Odile Morchoisne, Léa Pavan, Marion Landais, Thomas Davergne, Augustin Latourte, Pascal Richette, Johann Beaudreuil
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引用次数: 0

Abstract

Purpose: Little information exists on the potential differential response to functional restoration between non-specific chronic low back pain (NSCLBP) individuals with and those without Modic type 1 changes. Therefore, this case-control study investigated the response profile of NSCLBP patients with and without Modic type 1 changes undergoing functional restoration.

Methods: The present study included patients participating in a functional restoration program (day-hospital program lasting five weeks) at a French tertiary care center from 2009 to 2019. Each case with Modic type 1 changes was matched to one to two controls without Modic type 1 changes by sex, working incapacity, and lumbar spine surgery history. The primary effectiveness outcome was the Quebec Back Pain Disability Scale (QBPDS) score (0-100, with higher scores indicating higher disability). There were multiple secondary outcomes, such as subjective improvement and return to work.

Results: The study included 83 patients (cases: median [IQR] age 47.8 [11.6] years, 77.4% women; controls: median [IQR] age 46.0 [16.2] years, 75.0% women). At three months, there were no statistically significant differences between cases and controls in the QBPDS score (34.0 versus 31.5), subjective improvement (67.7% versus 69.2%), return to work in those who were not working at the inclusion (72.7% versus 52.6%), and the consumption of different analgesics.

Conclusion: The response profile of NSCLBP adults undergoing functional restoration did not statistically differ between the groups with and without Modic type 1 changes. These findings suggest that patients may benefit from such a program irrespective of their Modic type 1 status.

非特异性慢性腰痛Modic 1型改变对功能恢复的响应。
目的:关于非特异性慢性腰痛(NSCLBP)患者在功能恢复方面的潜在差异反应,有和没有Modic 1型变化的信息很少。因此,本病例对照研究探讨了有无Modic 1型改变的NSCLBP患者在功能恢复过程中的反应情况。方法:本研究纳入了2009年至2019年在法国三级医疗中心参加功能恢复计划(持续五周的日间住院计划)的患者。根据性别、工作能力和腰椎手术史,每个Modic 1型改变的病例与一到两个没有Modic 1型改变的对照组相匹配。主要疗效指标为魁北克背痛残疾量表(QBPDS)评分(0-100分,得分越高,残疾程度越高)。有多个次要结果,如主观改善和重返工作岗位。结果:纳入83例患者(例数:中位[IQR]年龄47.8[11.6]岁,77.4%为女性;对照组:中位[IQR]年龄46.0[16.2]岁,75.0%为女性)。三个月时,病例与对照组在QBPDS评分(34.0比31.5)、主观改善(67.7%比69.2%)、纳入组时不工作的患者重返工作岗位(72.7%比52.6%)和不同镇痛药的使用方面无统计学差异。结论:接受功能恢复的成人NSCLBP患者的疗效在Modic 1型改变组和未改变组之间无统计学差异。这些发现表明,患者可能受益于这样的方案,无论他们的Modic 1型状态。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
European Spine Journal
European Spine Journal 医学-临床神经学
CiteScore
4.80
自引率
10.70%
发文量
373
审稿时长
2-4 weeks
期刊介绍: "European Spine Journal" is a publication founded in response to the increasing trend toward specialization in spinal surgery and spinal pathology in general. The Journal is devoted to all spine related disciplines, including functional and surgical anatomy of the spine, biomechanics and pathophysiology, diagnostic procedures, and neurology, surgery and outcomes. The aim of "European Spine Journal" is to support the further development of highly innovative spine treatments including but not restricted to surgery and to provide an integrated and balanced view of diagnostic, research and treatment procedures as well as outcomes that will enhance effective collaboration among specialists worldwide. The “European Spine Journal” also participates in education by means of videos, interactive meetings and the endorsement of educative efforts. Official publication of EUROSPINE, The Spine Society of Europe
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