Prognostic value of contrast-enhanced ultrasound in dogs with acute renal injury treated with haemodialysis.

IF 1.8 3区农林科学 Q2 VETERINARY SCIENCES

Veterinary Record Pub Date : 2025-01-22 DOI:10.1002/vetr.4959

Caterina Puccinelli, Ilaria Lippi, Tina Pelligra, Simonetta Citi

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引用次数: 0

Abstract

Background: It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast-enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).

Methods: Dogs diagnosed with AKI or AKI/CKD were prospectively enrolled in the study. For all dogs, CEUS was performed at admission (T0). In addition, in haemodialysis-treated dogs, it was performed after the first dialysis (T1) and 7 days (T7) and 30 days (T30) after admission.

Results: A total of 41 dogs were enrolled, of which 30 were treated with haemodialysis and 11 received medical therapy. No significant difference was found between CEUS values at T0 in surviving and non-surviving patients after haemodialysis. A significant difference in cortical peak enhancement intensity (PI) values was found between T0, T1, T7 and T30, with the highest PI value at T0, a significant reduction at T1 and a progressive reduction in subsequent checks. There were no significant differences in CEUS parameters at T0 between patients with AKI and AKI/CKD.

Limitations: AKI aetiology was unknown in most cases, which limits the generalisability of the findings. Furthermore, the small sample size means that the statistical analysis is likely underpowered.

Conclusion: CEUS could be helpful in evaluating of the prognosis of dogs with AKI during haemodialysis.

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来源期刊

Veterinary Record 农林科学-兽医学

CiteScore

2.10

自引率

9.10%

发文量

1181

审稿时长

6-12 weeks

期刊介绍： Veterinary Record (branded as Vet Record) is the official journal of the British Veterinary Association (BVA) and has been published weekly since 1888. It contains news, opinion, letters, scientific reviews and original research papers and communications on a wide range of veterinary topics, along with disease surveillance reports, obituaries, careers information, business and innovation news and summaries of research papers in other journals. It is published on behalf of the BVA by BMJ Group.