[A CASE OF TESTICULAR TUMOR UNDER CONSIDERATION FOR PARTIAL ORCHIECTOMY THROUGH RAPID INTRAOPERATIVE DIAGNOSIS].

Jurii Karibe, Teppei Takeshima, Takashi Kawahara, Eren Iwasa, Takayuki Hirano, Yushi Araki, Daiji Takamoto, Hiroaki Ishida, Kimito Osaka, Jun-Ichi Teranishi, Yasushi Yumura, Hiroji Uemura
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Abstract

A 35-year-old man visited a local doctor for continuing analysis of his infertility. Semen analysis revealed azoospermia while an ultrasonography detected a right testicular tumor with a diameter of 10 mm. A blood test was negative for tumor markers. Magnetic resonance imaging showed a 1-cm tumor in the right testis and atrophy of the left testis. A testicular tumor arising from a functional unilateral testis was discovered during infertility treatment for which the patient was referred to our hospital for fertility preservation. Right and left testicular volumes were 18 mL and 3 mL, respectively, and his serum testosterone level was 2.96 ng/mL. Noting the atrophy of the contralateral testicle, we proceeded with a rapid pathology diagnosis by partial testicular resection. If no evidence of tumor malignancy was found, the surgery would have been concluded with no further dissection. Since the patient was undergoing fertility treatment, the decision was made to take sperm from the extracted testicle to preserve his fertility, followed by orchiectomy. Because a seminoma was suspected through the rapid pathological diagnosis, the man eventually underwent higher orchiectomy and testicular sperm extraction. The final diagnosis was seminoma, followed by successful retrieval of a sufficient level of sperm. Post operative serum testosterone level was found to be 0.32 ng/mL, after which testosterone replacement therapy was introduced. Through rapid diagnosis of pathology, successful management and outcome were achieved in the case of testicular cancer combined with infertility.

[术中快速诊断考虑行部分睾丸切除术1例]。
一名35岁的男子去当地医生那里继续分析他的不孕症。精液分析显示无精子症,超声检查发现右侧睾丸肿瘤直径10mm。血液检查肿瘤标志物呈阴性。磁共振显示右侧睾丸1公分肿瘤,左侧睾丸萎缩。患者在治疗不孕症时发现功能性单侧睾丸肿瘤,并转诊至我院保存生育能力。左右睾丸体积分别为18 mL和3 mL,血清睾酮水平为2.96 ng/mL。注意到对侧睾丸萎缩,我们通过部分睾丸切除进行快速病理诊断。如果没有发现肿瘤恶性的证据,手术就会结束,不再进行进一步的解剖。由于患者正在接受生育治疗,因此决定从提取的睾丸中取出精子以保持其生育能力,然后进行睾丸切除术。由于通过快速病理诊断怀疑是精原细胞瘤,该男子最终接受了更高级别的睾丸切除术和睾丸精子提取。最终诊断为精原细胞瘤,随后成功地提取了足够水平的精子。术后血清睾酮水平为0.32 ng/mL,给予睾酮替代治疗。通过快速的病理诊断,睾丸癌合并不孕症的治疗和治疗取得了成功。
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