[SUCCESSFUL TREATMENT WITH mFOLFOX6 FOR URACHAL ADENOCARCINOMA WITH MULTIPLE LUNG METASTASIS: A CASE REPORT].

Rumiko Sugimura, Tadashi Tabei, Yuta Karibe, Takahiro Mitomi, Hiroki Takizawa, Makoto Funahashi, Junichi Ota
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Abstract

We report the case of a 41-year-old man who presented with gross hematuria and a bladder tumor on ultrasonography. Magnetic resonance imaging indicated a possible muscle-invasive bladder cancer or urachal carcinoma. Following transurethral resection of the bladder tumor, histopathological findings revealed an adenocarcinoma similar to colorectal cancer. The patient was diagnosed with an urachal carcinoma in the urinary bladder dome. Since multiple lung metastases were observed on computed tomography, and his serum carcinoembryonic antigen level was 116 ng/dL, his final diagnosis was a stage IVb urachal carcinoma. He received 11 courses of mFOLOX6, and underwent a laparoscopy-assisted partial cystectomy and pelvic lymph node dissection. Pathological examination confirmed negative surgical margins, but remained tumor cells were confirmed. The patient continued mFOLFOX6 treatment for 12 months postoperatively, with no disease progression observed.

mFOLFOX6成功治疗伴有多肺转移的尿管腺癌1例。
我们报告的情况下,41岁的男子谁提出肉眼血尿和膀胱肿瘤超声检查。磁共振显示可能为肌肉浸润性膀胱癌或尿管癌。经尿道膀胱肿瘤切除术后,组织病理学结果显示为类似结直肠癌的腺癌。患者被诊断为膀胱穹窿的尿管癌。由于计算机断层扫描发现多发肺转移,血清癌胚抗原116 ng/dL,最终诊断为IVb期尿路癌。他接受了11个疗程的mFOLOX6,并进行了腹腔镜辅助部分膀胱切除术和盆腔淋巴结清扫。病理检查证实手术缘阴性,但仍有肿瘤细胞。患者术后继续mFOLFOX6治疗12个月,未观察到疾病进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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