Management of a Left Anterior Descending Artery Aneurysm in Behçet's Disease: A Case Report.

Abstract

Behçet's disease (BD) is a chronic, relapsing, systemic vasculitis of unknown etiology that affects blood vessels of all sizes, potentially leading to severe complications such as coronary artery aneurysms. This report describes the case of a 33-year-old woman with BD who presented with recurrent chest pain. Imaging revealed a large saccular aneurysm in the left anterior descending artery. Management involved multiple percutaneous coronary interventions to stabilize the aneurysm, alongside infliximab, a tumor necrosis factor-alpha inhibitor, to control the underlying vasculitis. The patient has remained in clinical remission for over three years, providing additional evidence supporting the role of infliximab in addressing vascular complications in BD. This case highlights the challenges in managing coronary artery aneurysms in BD and emphasizes the need for further research into the long-term safety and efficacy of infliximab for such cases.