Behcet's disease in a tertiary eye hospital in Pakistan.

Therapeutic advances in rare disease Pub Date : 2025-01-18 eCollection Date: 2025-01-01 DOI:10.1177/26330040251314126
Tabish Ali Shalwani, Alishan Khowaja, Narmeen Punjwani
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Abstract

Behçet's disease is a kind of variable vessel vasculitis (VVV) and inflammatory systematic disease affecting various organs of the body. The cause of the disease is idiopathic but is most commonly genetic in origin. A positive skin prick test (dermatographia), genital sores, eye irritation, skin sores, and at least three episodes of mouth sores in a year confirm the diagnosis. Treatment may include immunosuppressive agents, immune modulators, and biological markers such as corticosteroids, immunosuppressants, and antibodies. We report a case of a 23-year-old male patient, presented in an outpatient clinic in a tertiary care eye hospital located in Pakistan. The patient reported sudden loss of vision in one eye and graduate loss of vision in the other eye. Ocular and systemic investigations were performed to correlate with clinical findings to reach a diagnosis. The patient was managed symptomatically and was put on corticosteroids. Our hospital is a research and postgraduate educational institution that deals with complex eye diseases. The range of investigations and clinical exams helped clinical decision-makers in evaluating the patient's diagnosis.

巴基斯坦一家三级眼科医院的白塞氏病。
behet病是一种累及全身各脏器的变异性血管炎(VVV)炎性全身性疾病。该疾病的病因是特发性的,但最常见的是遗传起源。皮肤点刺试验阳性(皮肤记录)、生殖器溃疡、眼睛刺激、皮肤溃疡和一年内至少三次口腔溃疡发作证实了诊断。治疗可包括免疫抑制剂、免疫调节剂和生物标志物,如皮质类固醇、免疫抑制剂和抗体。我们报告一例23岁的男性患者,在门诊诊所在三级保健眼科医院位于巴基斯坦。患者报告一只眼睛突然丧失视力,另一只眼睛逐渐丧失视力。进行眼部和全身检查,与临床表现相关联,以达到诊断。对患者进行了对症治疗并给予皮质类固醇治疗。我们医院是一个研究和研究生教育机构,处理复杂的眼病。调查和临床检查的范围帮助临床决策者评估患者的诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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