A Wearable Prototype Measuring PtcCO2 and SpO2.

Kleo Golemi, Evan Apinis, Isil Isiksalan, Vladimir Vakhter, Ulkuhan Guler
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Abstract

The proper functioning of the respiratory system is evaluated by monitoring the exchange of blood oxygen and carbon dioxide. While wearable devices for monitoring both blood oxygen and carbon dioxide are emerging, wearable carbon dioxide monitors remain relatively rare. This paper introduces a novel wearable prototype that integrates the measurement of transcutaneous carbon dioxide and peripheral blood oxygen saturation on a miniaturized custom-designed printed circuit board. The device employs a fluorescent sensing film consisting of two distinct luminophore types and utilizes the time-domain dual lifetime referencing technique to enhance measurement accuracy by mitigating the effects of confounding factors. Thorough testing on human subjects validated the prototype's functionality, comparing its performance against commercial clinical devices. The prototype effectively tracked changes in transcutaneous carbon dioxide induced by hyperventilation, with a resolution as low as 1 mmHg. Additionally, blood oxygen saturation measurements were tested on human subjects to compare our prototypes' performance to that of clinical devices. The results confirm the potential of the proposed novel wearable for prolonged use with minimal maintenance and underscore its significance in advancing wearable health monitoring technologies.

一种可穿戴式PtcCO2和SpO2测量样机。
呼吸系统的正常功能是通过监测血氧和二氧化碳的交换来评估的。虽然监测血氧和二氧化碳的可穿戴设备正在出现,但可穿戴二氧化碳监测仪仍然相对罕见。本文介绍了一种新型可穿戴原型,该原型集成了经皮二氧化碳和外周血氧饱和度的测量,该测量集成在小型化定制设计的印刷电路板上。该装置采用由两种不同发光团类型组成的荧光传感膜,并利用时域双寿命参考技术,通过减轻混杂因素的影响来提高测量精度。对人体的全面测试验证了原型的功能,并将其性能与商业临床设备进行了比较。该原型有效地跟踪了由过度通气引起的经皮二氧化碳的变化,分辨率低至1mmhg。此外,还对人体进行了血氧饱和度测量,以将我们的原型设备的性能与临床设备的性能进行比较。结果证实了所提出的新型可穿戴设备的潜力,即以最少的维护时间长时间使用,并强调了其在推进可穿戴健康监测技术方面的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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