Effectiveness of non-pharmacological interventions to prevent enteral nutrition intolerance in ICU patients: A network meta-analysis.

IF 3 3区 医学 Q1 NURSING
Ni Yang, Yuan Xu, Xinyi Zhou, Shuli Guo, Haibo Deng, Jianhua Sun, Ying Liu, Manna Shao, Yufen Ma
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引用次数: 0

Abstract

Background: Enteral nutrition is beneficial for improving the clinical outcomes of intensive care unit patients. However, enteral nutrition intolerance is a common complication in intensive care unit patients undergoing enteral nutrition.

Aims: We aimed to assess the effectiveness of non-pharmacological interventions in preventing enteral nutrition intolerance in intensive care unit patients and to identify the optimal non-pharmacological interventions.

Study design: Seven databases were searched to obtain randomized controlled trials involving non-pharmacological interventions to prevent enteral nutrition intolerance in intensive care unit patients. Network meta-analysis was performed using Stata18.0 software, and the integrated data were investigated with odds ratio (OR) and 95% confidence interval (95% CI).

Results: A total of 16 randomized controlled trials involving 10 non-pharmacological interventions and 1765 intensive care unit patients were included. Compared with routine enteral nutrition care, network meta-analysis showed that bundled care [OR = 0.93, 95% CI (0.32-1.53)] (p = .003), intra-abdominal pressure monitoring [OR = 1.68, 95%CI (1.19-2.16)] (p < .001), acupuncture [OR = 2.69, 95%CI (1.64-3.73)] (p < .001), pectin-added intermittent enteral nutrition [OR = 1.13, 95%CI (0.48-1.77)] (p = .001), multidisciplinary nutritional treatment model [OR = 1.98, 95%CI (0.87-3.10)] (p < .001), abdominal massage [OR = 2.42, 95%CI (1.50-3.34)] (p < .001) and intermittent feeding with semisolid nutrients [OR = 2.08, 95%CI (0.19-3.97)] (p = .031) were effective in preventing enteral nutrition intolerance in intensive care unit patients. The ranking probabilities of the interventions indicated that acupuncture (89.4%) was the optimal non-pharmacological intervention for preventing enteral nutrition intolerance in intensive care unit patients, followed by abdominal massage (83.4%).

Conclusions: Acupuncture and abdominal massage are recommended to prevent enteral nutrition intolerance in intensive care unit patients. Moreover, more high-quality trials are needed to investigate the reliability of evidence levels for different non-pharmacological interventions.

Relevance to clinical practice: This study provided evidence for intensive care nurses that acupuncture is the optimal intervention to improve enteral nutrition intolerance in intensive care unit patients among the 10 interventions. However, unique clinical circumstances should be considered. Therefore, we recommend that intensive care nurses also use abdominal massage when acupuncture is not available.

非药物干预预防ICU患者肠内营养不耐受的有效性:网络荟萃分析。
背景:肠内营养有利于改善重症监护病人的临床预后。然而,肠内营养不耐受是重症监护病房患者接受肠内营养的常见并发症。目的:我们旨在评估非药物干预措施在预防重症监护病房患者肠内营养不耐受方面的有效性,并确定最佳的非药物干预措施。研究设计:检索了7个数据库,以获得涉及非药物干预预防重症监护病房患者肠内营养不耐受的随机对照试验。采用Stata18.0软件进行网络meta分析,采用优势比(OR)和95%置信区间(95% CI)对综合数据进行调查。结果:共纳入16项随机对照试验,涉及10项非药物干预措施,重症监护病房患者1765例。与常规肠内营养护理相比,网络荟萃分析显示,捆绑式护理[OR = 0.93, 95%CI (0.32-1.53)] (p = 0.003)、腹内压监测[OR = 1.68, 95%CI (1.19-2.16)] (p < 0.001)、针刺[OR = 2.69, 95%CI (1.64-3.73)] (p < 0.001)、添加果胶的间歇肠内营养[OR = 1.13, 95%CI (0.48-1.77)] (p = 0.001)、多学科营养治疗模式[OR = 1.98, 95%CI (0.87-3.10)] (p < 0.001)、腹部按摩[OR = 2.42,95%CI (1.50 ~ 3.34)] (p < 0.001)和间歇喂食半固体营养物[OR = 2.08, 95%CI (0.19 ~ 3.97)] (p = 0.031)可有效预防重症监护病房患者肠内营养不耐受。干预措施的排序概率表明,针刺(89.4%)是预防重症监护病房患者肠内营养不耐受的最佳非药物干预措施,其次是腹部按摩(83.4%)。结论:推荐针刺加腹部按摩预防重症监护室患者肠内营养不耐受。此外,需要更多高质量的试验来调查不同非药物干预措施的证据水平的可靠性。与临床实践的相关性:本研究为重症监护护士提供了证据,在10种干预措施中,针灸是改善重症监护病房患者肠内营养不耐受的最佳干预措施。然而,独特的临床情况应予以考虑。因此,我们建议重症监护护士在没有针灸的情况下也使用腹部按摩。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.00
自引率
13.30%
发文量
109
审稿时长
>12 weeks
期刊介绍: Nursing in Critical Care is an international peer-reviewed journal covering any aspect of critical care nursing practice, research, education or management. Critical care nursing is defined as the whole spectrum of skills, knowledge and attitudes utilised by practitioners in any setting where adults or children, and their families, are experiencing acute and critical illness. Such settings encompass general and specialist hospitals, and the community. Nursing in Critical Care covers the diverse specialities of critical care nursing including surgery, medicine, cardiac, renal, neurosciences, haematology, obstetrics, accident and emergency, neonatal nursing and paediatrics. Papers published in the journal normally fall into one of the following categories: -research reports -literature reviews -developments in practice, education or management -reflections on practice
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