Validation of clearcalc for efficient patient specific QA.

IF 1.1 4区 医学 Q4 ONCOLOGY
Ignatius Komakech, Denis Okello, Awusi Kavuma, Bonny Abal, Annette Wygoda
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引用次数: 0

Abstract

Uganda's only radiotherapy center is a very busy facility treating about 210 patients daily on three linear accelerators making it sometimes hard to have machine time for pretreatment QAs. This study was aimed at validating an independent calculation software, ClearCalc (ICS) for second checks of the treatment planning system (TPS) calculations. The validation of ICS started with simple phantom test plans consisting of square, irregular, open and wedged fields designed in the TPS and measured in phantoms. Doses and monitor units (MUs) calculated by ICS were compared with TPS calculated doses and with measured doses. ICS was then validated on clinically approved treatment plans: comparison with TPS calculations and with pretreatment QA measurements performed with electronic portal imaging devices (EPIDs) and analyzed using Gamma passing criteria of 3%/3 mm and 3%/2 mm. Results for test plans were within the passing level of 3.0% except for 2 outliers (-3.1% and 3.1%). As for the clinically approved treatment plans, they show good agreement between MUs (0.2 ± 1.8%), reference point doses (0.2 ±1.5%) and mean PTV doses (0.5 ± 1.4%). ICS calculated (3D) mean gamma pass rates were 98.1±1.6% and 98.4±1.0% for 3%/2 mm and 3%/3 mm criteria. No correlation was seen between gamma analysis results from ICS and EPID. This study validated ClearCalc on phantom and clinically approved plans. The result show that ICS based patients specific QA is quick, promising and potentially allows significant time saving that can be utilized for patient treatments.

验证clearcalc对患者特异性QA的有效性。
乌干达唯一的放射治疗中心是一个非常繁忙的设施,每天用三个线性加速器治疗大约210名患者,有时很难有机器时间进行预处理QAs。本研究旨在验证一种独立的计算软件ClearCalc (ICS),用于治疗计划系统(TPS)计算的二次检查。ICS的验证从简单的模拟测试计划开始,包括在TPS中设计的方形、不规则、开放和楔形场,并在模拟中测量。将ICS计算的剂量和监测单位(MUs)与TPS计算剂量和测量剂量进行比较。然后在临床批准的治疗方案上验证ICS:与TPS计算和使用电子门静脉成像设备(EPIDs)进行的预处理QA测量进行比较,并使用3%/ 3mm和3%/ 2mm的Gamma通过标准进行分析。除2个异常值(-3.1%和3.1%)外,测试计划的结果均在3.0%的合格水平内。在临床批准的治疗方案中,MUs(0.2±1.8%)、参考点剂量(0.2±1.5%)和平均PTV剂量(0.5±1.4%)具有良好的一致性。ICS计算的(3D)平均伽马通过率在3%/2 mm和3%/3 mm标准下分别为98.1±1.6%和98.4±1.0%。ICS和EPID的伽马分析结果之间没有相关性。该研究验证了ClearCalc对幻影的治疗效果和临床批准的方案。结果表明,基于ICS的患者特异性QA是快速的,有前途的,并且可能节省大量的时间,可以用于患者的治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medical Dosimetry
Medical Dosimetry 医学-核医学
CiteScore
2.40
自引率
0.00%
发文量
51
审稿时长
34 days
期刊介绍: Medical Dosimetry, the official journal of the American Association of Medical Dosimetrists, is the key source of information on new developments for the medical dosimetrist. Practical and comprehensive in coverage, the journal features original contributions and review articles by medical dosimetrists, oncologists, physicists, and radiation therapy technologists on clinical applications and techniques of external beam, interstitial, intracavitary and intraluminal irradiation in cancer management. Articles dealing primarily with physics will be reviewed by a specially appointed team of experts in the field.
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