Tracheostomy as a Management Option After Listing for Pediatric Cardiac Transplantation.

IF 1.4 4区 医学 Q3 PEDIATRICS
Elisabeth Day, Deborah Cross, David Crossland, Jason Powell, Emma Simpson
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Abstract

Background: Children with end-stage heart failure listed for cardiac transplantation may require mechanical ventilation and/or circulatory support whilst awaiting transplantation. A subgroup of these patients is unable to wean off mechanical ventilator support and undergo tracheostomy to enhance quality of life and allow de-escalation of intensive care. There is limited evidence of the use of tracheostomy associated with pediatric cardiac transplantation. We describe outcomes to better inform future management of these patients.

Methods: A single-centre, retrospective study was performed, assessing all pediatric patients (< 18 years) listed for cardiac transplant from 2006 to 2017. We assessed background demographics and outcomes, including cardiac diagnosis, complications, insertion of ventricular assist device and survival. We identified patients who underwent tracheostomy after listing and compared this group with non-tracheostomised patients.

Results: Two hundred and eleven patients were listed for cardiac transplant, of whom 44 (21%) underwent tracheostomy after listing. The main indication for tracheostomy was failure to wean from mechanical ventilation (36%). Complications after tracheostomy included localized infection, granuloma, obstruction and hemorrhage, but were generally minor. Median time for tracheostomy decannulation was 75 days. When comparing tracheostomy versus non-tracheostomy patients, there were no significant differences in age, weight or time to transplant. Survival was comparable between the non-tracheostomy and tracheostomy groups at 1-year, 97% versus 94% respectively.

Conclusion: There is no evidence from our study that patients awaiting cardiac transplant who undergo tracheostomy have significant complications or reduced survival. Tracheostomy is usually a short-term measure and should be considered in the management of children receiving prolonged ventilation around the time of cardiac transplantation.

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气管切开术作为儿科心脏移植后的治疗选择。
背景:被列为心脏移植的终末期心力衰竭儿童在等待移植期间可能需要机械通气和/或循环支持。这些患者中的一个亚组无法脱离机械呼吸机支持并接受气管切开术以提高生活质量并允许减少重症监护。气管切开术与儿童心脏移植相关的证据有限。我们描述结果是为了更好地为这些患者的未来管理提供信息。方法:进行单中心回顾性研究,评估所有儿科患者(结果:211例患者被列入心脏移植,其中44例(21%)在入选后接受了气管切开术。气管切开术的主要指征是无法脱离机械通气(36%)。气管造口术后并发症包括局部感染、肉芽肿、梗阻和出血,但一般较轻。气管切开脱管的中位时间为75天。当比较气管造口术与非气管造口术患者时,年龄、体重或移植时间没有显著差异。非气管切开术组和气管切开术组1年生存率相当,分别为97%和94%。结论:我们的研究没有证据表明等待心脏移植的患者行气管切开术会有明显的并发症或降低生存率。气管切开术通常是一种短期措施,在处理心脏移植前后接受长时间通气的儿童时应考虑气管切开术。
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来源期刊
Pediatric Transplantation
Pediatric Transplantation 医学-小儿科
CiteScore
2.90
自引率
15.40%
发文量
216
审稿时长
3-8 weeks
期刊介绍: The aim of Pediatric Transplantation is to publish original articles of the highest quality on clinical experience and basic research in transplantation of tissues and solid organs in infants, children and adolescents. The journal seeks to disseminate the latest information widely to all individuals involved in kidney, liver, heart, lung, intestine and stem cell (bone-marrow) transplantation. In addition, the journal publishes focused reviews on topics relevant to pediatric transplantation as well as timely editorial comment on controversial issues.
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