Exploring the potential of MRM-IDA-EPI method in mass spectrometry for exposomic analysis: a commentary.

IF 4.8 2区医学 Q1 TOXICOLOGY

Archives of Toxicology Pub Date : 2025-01-17 DOI:10.1007/s00204-025-03958-9

Ravikumar Jagani, Jasmin Chovatiya, Hiraj Patel, Syam S Andra

引用次数: 0

Abstract

Exposomics is a field that studies environmental exposures and their impact on human health. The MRM-IDA-EPI method, which combines targeted and untargeted mass spectrometry methods, is useful for identifying and quantifying biomarkers in various biological matrices. The method's accuracy and precision in forensic toxicological screening suggest potential applications for detecting low-level environmental exposures. It can help detect and understand environmental exposures, explain their metabolic processes, and assess their impact on human health more effectively.

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探索MRM-IDA-EPI方法在暴露体分析质谱中的潜力：评论。

暴露学是研究环境暴露及其对人类健康影响的一个领域。MRM-IDA-EPI方法结合了靶向和非靶向质谱方法，可用于鉴定和定量各种生物基质中的生物标志物。该方法在法医毒理学筛选中的准确性和精密度为检测低水平环境暴露提供了潜在的应用。它可以帮助检测和了解环境暴露，解释其代谢过程，并更有效地评估其对人类健康的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Toxicology 医学-毒理学

CiteScore

11.60

自引率

4.90%

发文量

218

审稿时长

1.5 months

期刊介绍： Archives of Toxicology provides up-to-date information on the latest advances in toxicology. The journal places particular emphasis on studies relating to defined effects of chemicals and mechanisms of toxicity, including toxic activities at the molecular level, in humans and experimental animals. Coverage includes new insights into analysis and toxicokinetics and into forensic toxicology. Review articles of general interest to toxicologists are an additional important feature of the journal.