Trajectories and Predictors of Frailty in Patients With Heart Failure: A Longitudinal Study.

IF 3.2 3区 医学 Q1 NURSING
Mei Yang, Xiuting Zhang, Wenjie Fang, Yilin Zhang, Xiuzhen Fan
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Abstract

Aim: This study aimed to identify the heterogeneous trajectories of frailty and determine the predictors of distinct trajectories in patients with heart failure.

Design: A longitudinal study.

Methods: A total of 253 patients with heart failure were recruited at the cardiology department of a tertiary hospital between February and December 2023. Frailty was assessed at baseline, 1 and 4 months after discharge. Patients' sociodemographic characteristics, physical symptoms, nutritional status, psychological distress, illness perception and social networks were obtained at baseline using a structured questionnaire. Group-based trajectory modelling was performed to identify the heterogeneity of the trajectories of frailty. Multiple logistic regression and decision tree models were used to explore the predictors of heterogeneous trajectories of frailty.

Results: Three distinct trajectories of frailty were identified in patients with heart failure: low frailty with high-degree improvement group (46.2%), moderate frailty with high-degree improvement group (41.1%) and high frailty with low-degree improvement group (12.6%). Multiple logistic regression analysis showed that physical symptoms, nutritional status, illness perception and employment status were entered as independent predictors of heterogeneous trajectories of frailty. The decision tree model demonstrated that physical symptoms were the primary predictors, followed by nutritional status, illness perception and psychological distress.

Conclusions: Three distinct categories of frailty trajectories were identified in patients with heart failure. Physical symptoms, nutritional status, psychological distress, illness perception and employment status were independent predictors of heterogeneous trajectories of frailty, with physical symptoms being the most important predictor.

Implication to clinical practice: Dynamic frailty assessment is recommended. Interventions aimed at alleviating physical symptoms, psychological distress and negative illness perception, and improving nutritional status may be conducive to delaying or reversing frailty in patients with heart failure, particularly in unemployed individuals.

Reporting method: The reporting followed the STROBE guideline.

Patient or public contributions: No patient or public contribution.

心力衰竭患者衰弱的轨迹和预测因素:一项纵向研究。
目的:本研究旨在确定心力衰竭患者虚弱的异质性轨迹,并确定不同轨迹的预测因素。设计:纵向研究。方法:于2023年2月至12月在某三级医院心内科招募心衰患者253例。在基线、出院后1个月和4个月评估虚弱程度。患者的社会人口学特征、身体症状、营养状况、心理困扰、疾病感知和社会网络在基线时使用结构化问卷。采用基于组的轨迹建模来确定脆弱轨迹的异质性。采用多元逻辑回归和决策树模型来探讨脆弱性异质性轨迹的预测因子。结果:心力衰竭患者有三种不同的衰弱轨迹:轻度衰弱伴高度改善组(46.2%)、中度衰弱伴高度改善组(41.1%)和高度衰弱伴低程度改善组(12.6%)。多元logistic回归分析显示,身体症状、营养状况、疾病认知和就业状况是异质性衰弱轨迹的独立预测因子。决策树模型显示,身体症状是主要预测因子,其次是营养状况、疾病感知和心理困扰。结论:心力衰竭患者有三种不同的衰弱轨迹。身体症状、营养状况、心理困扰、疾病感知和就业状况是虚弱异质性轨迹的独立预测因子,其中身体症状是最重要的预测因子。对临床实践的启示:推荐动态衰弱评估。旨在减轻身体症状、心理困扰和消极疾病感知以及改善营养状况的干预措施可能有助于延缓或逆转心力衰竭患者,特别是失业者的虚弱。报告方法:报告遵循STROBE指南。患者或公众捐款:没有患者或公众捐款。
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来源期刊
CiteScore
6.40
自引率
2.40%
发文量
0
审稿时长
2 months
期刊介绍: The Journal of Clinical Nursing (JCN) is an international, peer reviewed, scientific journal that seeks to promote the development and exchange of knowledge that is directly relevant to all spheres of nursing practice. The primary aim is to promote a high standard of clinically related scholarship which advances and supports the practice and discipline of nursing. The Journal also aims to promote the international exchange of ideas and experience that draws from the different cultures in which practice takes place. Further, JCN seeks to enrich insight into clinical need and the implications for nursing intervention and models of service delivery. Emphasis is placed on promoting critical debate on the art and science of nursing practice. JCN is essential reading for anyone involved in nursing practice, whether clinicians, researchers, educators, managers, policy makers, or students. The development of clinical practice and the changing patterns of inter-professional working are also central to JCN''s scope of interest. Contributions are welcomed from other health professionals on issues that have a direct impact on nursing practice. We publish high quality papers from across the methodological spectrum that make an important and novel contribution to the field of clinical nursing (regardless of where care is provided), and which demonstrate clinical application and international relevance.
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