Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report.

Xianghui Li, Yong Wei, Zhuren Ruan, Gao Wei, Zhijian Yao
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Abstract

Purpose: Keloid tissue represents an abnormal proliferation of fibroblasts, typically resulting from skin injury. These lesions can lead to significant physiological dysfunction and aesthetic concerns, particularly when located on the face. Traditional treatments, such as intralesional injections, laser therapy, and surgical excision, have shown limited efficacy and are associated with high recurrence rates.

Materials and methods: In a recent case, a 19-year-old male with a keloid on the upper lip did not respond to local injections of triamcinolone acetonide (TAC) or carbon dioxide ablative fractional resurfacing laser therapy.

Results: A combined treatment approach involving trepanation and superficial radiotherapy successfully flattened the keloid tissue, with no recurrence observed during a 3-year follow-up period.

Conclusions: This case underscores the potential efficiency and safety of combined therapeutic interventions and contributes valuable evidence towards the development of novel treatment strategies for keloids.

上唇瘢痕疙瘩的成功治疗:病例报告。
目的:瘢痕疙瘩组织是指成纤维细胞的异常增生,通常由皮肤损伤引起。这些病变可导致显著的生理功能障碍和审美问题,特别是当它位于面部时。传统的治疗方法,如病灶内注射、激光治疗和手术切除,疗效有限,且复发率高。材料和方法:在最近的一个病例中,一名19岁的男性上唇有瘢痕瘤,局部注射曲安奈德(TAC)或二氧化碳消融分次激光表面置换治疗无效。结果:采用钻孔和浅表放射治疗的联合治疗方法成功地使瘢痕疙瘩组织变平,3年随访期间未见复发。结论:该病例强调了联合治疗干预的潜在有效性和安全性,并为瘢痕疙瘩的新治疗策略的发展提供了有价值的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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