{"title":"Newer Diagnostic Virological Markers for Hepatitis B Virus Infection.","authors":"Reshu Agarwal, Ekta Gupta, Jasmine Samal, Sheetalnath Rooge, Akshita Gupta","doi":"10.5005/jp-journals-10018-1450","DOIUrl":null,"url":null,"abstract":"<p><p>Chronic Hepatitis B (CHB) remains a major public health problem, leading to various complications such as liver fibrosis, cirrhosis, and hepatocellular carcinoma. The existing diagnostic markers for Hepatitis B virus (HBV) are limited in distinguishing different CHB phases and intra-hepatic viral replication activity. In the past few years, several non-invasive potential blood markers that reflect viral intra-hepatic replicative state more accurately have been in progress and are gaining importance. Despite substantial efforts, the clinical utility of these new markers in CHB management is limited and unexplored. Therefore, in this review, we will discuss some of the newer HBV markers, their potential role in the diagnosis and monitoring of CHB patients.</p><p><strong>How to cite this article: </strong>Agarwal R, Gupta E, Samal J, <i>et al.</i> Newer Diagnostic Virological Markers for Hepatitis B Virus Infection. Euroasian J Hepato-Gastroenterol 2024;14(2):214-220.</p>","PeriodicalId":516317,"journal":{"name":"Euroasian journal of hepato-gastroenterology","volume":"14 2","pages":"214-220"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11714116/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Euroasian journal of hepato-gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5005/jp-journals-10018-1450","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/27 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Chronic Hepatitis B (CHB) remains a major public health problem, leading to various complications such as liver fibrosis, cirrhosis, and hepatocellular carcinoma. The existing diagnostic markers for Hepatitis B virus (HBV) are limited in distinguishing different CHB phases and intra-hepatic viral replication activity. In the past few years, several non-invasive potential blood markers that reflect viral intra-hepatic replicative state more accurately have been in progress and are gaining importance. Despite substantial efforts, the clinical utility of these new markers in CHB management is limited and unexplored. Therefore, in this review, we will discuss some of the newer HBV markers, their potential role in the diagnosis and monitoring of CHB patients.
How to cite this article: Agarwal R, Gupta E, Samal J, et al. Newer Diagnostic Virological Markers for Hepatitis B Virus Infection. Euroasian J Hepato-Gastroenterol 2024;14(2):214-220.
慢性乙型肝炎（CHB）仍然是一个主要的公共卫生问题，导致各种并发症，如肝纤维化，肝硬化和肝细胞癌。现有的乙型肝炎病毒（HBV）诊断标志物在区分不同的CHB期和肝内病毒复制活性方面是有限的。在过去的几年中，一些更准确地反映病毒肝内复制状态的非侵入性潜在血液标志物已经取得进展，并且越来越重要。尽管付出了巨大的努力，但这些新标志物在慢性乙型肝炎治疗中的临床应用仍然有限且未被探索。因此，在这篇综述中，我们将讨论一些较新的HBV标志物及其在慢性乙型肝炎患者诊断和监测中的潜在作用。引用方式：Agarwal R， Gupta E, Samal J，等。乙型肝炎病毒感染的新诊断病毒学标志物。中华肝病与胃肠病杂志；2009;14(2):214-220。
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