Examining the Potential Impact of Recreational Cannabis Legalization on Individuals Receiving Treatment for Substance Use Disorder: An Interrupted Time Series Study in Guelph, Ontario, Canada.

Cannabis (Albuquerque, N.M.) Pub Date : 2024-12-12 eCollection Date: 2024-01-01 DOI:10.26828/cannabis/2024/000260
Emily M Britton, Radia Taisir, Alysha Cooper, Yao Li, Sarah Sousa, Yelena Chorny, James MacKillop, Mary Jean Costello
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Abstract

Objective: The present research evaluated the impact of legalizing recreational cannabis among individuals with substance use disorders (SUDs) who may already use cannabis at high rates.

Method: Using an interrupted time series study design, we evaluated the potential impact of legalizing recreational cannabis among individuals seeking treatment for SUD within a hospital-based treatment setting in Guelph, Ontario. We examined 2,925 individuals who entered an inpatient SUD treatment program between April 2017 and December 2021. We performed segmented regression analyses using both the date of cannabis legalization and the date of edibles legalization as the interruption time point. We also performed stratified analyses to examine potential sex differences.

Results: We found no significant changes in the frequency of cannabis use using either of the interruption time points. However, among the subsample who had used cannabis, there was evidence of increasing CUD severity post-legalization of edibles, as well as an overall decreasing trend in readiness to quit over time. Stratified analyses also suggested possible sex differences in frequency of cannabis use, CUD severity, and readiness to quit.

Conclusions: Results point to some small but potentially important impacts of recreational cannabis legalization that may only continue with time. Nevertheless, there is a need to continue to monitor cannabis use trends over time to understand any potential lagged effects.

研究休闲大麻合法化对接受物质使用障碍治疗的个人的潜在影响:加拿大安大略省圭尔夫的一项中断时间序列研究。
目的:本研究评估了娱乐性大麻合法化对可能已经高使用率使用大麻的物质使用障碍(sud)个体的影响。方法:采用中断时间序列研究设计,我们评估了娱乐性大麻合法化对在安大略省圭尔夫的医院治疗环境中寻求SUD治疗的个人的潜在影响。我们检查了2925名在2017年4月至2021年12月期间进入住院SUD治疗计划的患者。我们使用大麻合法化日期和可食用食品合法化日期作为中断时间点进行分段回归分析。我们还进行了分层分析,以检查潜在的性别差异。结果:我们发现使用任何中断时间点的大麻使用频率没有显着变化。然而,在使用过大麻的子样本中,有证据表明,在大麻合法化后,CUD的严重程度有所增加,而且随着时间的推移,戒烟的意愿总体呈下降趋势。分层分析还表明,在大麻使用频率、CUD严重程度和戒烟意愿方面可能存在性别差异。结论:研究结果表明,随着时间的推移,娱乐性大麻合法化可能会产生一些微小但潜在的重要影响。尽管如此,仍有必要继续监测大麻使用趋势,以了解任何潜在的滞后效应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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