Ferroptosis and tumor immunity.

Q3 Medicine

中南大学学报(医学版) Pub Date : 2024-08-28 DOI:10.11817/j.issn.1672-7347.2024.240389

Qian Tao, Nian Liu, Jing Chen, Jie Wu, Jie Li, Xiang Chen, Cong Peng

引用次数: 0

Abstract

Ferroptosis is a unique form of cell death driven by iron-dependent lipid peroxidation, with regulatory mechanisms involving metabolic dysregulation and imbalance in redox systems. Ferroptosis is closely related to various immune cells in the tumor immune microenvironment, including both anti-tumor and pro-tumor immune cells, and it demonstrates significant potential in tumor immunotherapy. A systematic review of the regulatory mechanisms of ferroptosis and its relationship with immune cells can provide deeper insights into its application prospects in tumor immunotherapy.

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铁下垂与肿瘤免疫。

铁死亡是一种由铁依赖性脂质过氧化驱动的独特细胞死亡形式，其调节机制涉及氧化还原系统的代谢失调和不平衡。铁下垂与肿瘤免疫微环境中的多种免疫细胞密切相关，包括抗肿瘤和促肿瘤免疫细胞，在肿瘤免疫治疗中具有重要的潜力。对铁下垂的调控机制及其与免疫细胞的关系进行系统综述，可以为其在肿瘤免疫治疗中的应用前景提供更深入的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中南大学学报(医学版) Medicine-Medicine (all)

CiteScore

1.00

自引率

0.00%

发文量

8237

期刊介绍： Journal of Central South University (Medical Sciences), founded in 1958, is a comprehensive academic journal of medicine and health sponsored by the Ministry of Education and Central South University. The journal has been included in many important databases and authoritative abstract journals at home and abroad, such as the American Medline, Pubmed and its Index Medicus (IM), the Netherlands Medical Abstracts (EM), the American Chemical Abstracts (CA), the WHO Western Pacific Region Medical Index (WPRIM), and the Chinese Science Citation Database (Core Database) (CSCD); it is a statistical source journal of Chinese scientific and technological papers, a Chinese core journal, and a "double-effect" journal of the Chinese Journal Matrix; it is the "2nd, 3rd, and 4th China University Excellent Science and Technology Journal", "2008 China Excellent Science and Technology Journal", "RCCSE China Authoritative Academic Journal (A+)" and Hunan Province's "Top Ten Science and Technology Journals". The purpose of the journal is to reflect the new achievements, new technologies, and new experiences in medical research, medical treatment, and teaching, report new medical trends at home and abroad, promote academic exchanges, improve academic standards, and promote scientific and technological progress.