Observational study of venous leg ulcer treated with a native collagen-alginate dressing and the impact on wound-related quality of life.

IF 1 4区医学 Q4 DERMATOLOGY

Wound management & prevention Pub Date : 2024-12-01 DOI:10.25270/wmp.23113

Alisha Oropallo, Amit Rao, Sally Kaplan, Farisha Baksh, Christina Del Pin, Julie Isgro

{"title":"Observational study of venous leg ulcer treated with a native collagen-alginate dressing and the impact on wound-related quality of life.","authors":"Alisha Oropallo, Amit Rao, Sally Kaplan, Farisha Baksh, Christina Del Pin, Julie Isgro","doi":"10.25270/wmp.23113","DOIUrl":null,"url":null,"abstract":"Background: Venous leg ulcers (VLUs) are associated with various physical and social adverse effects for patients but also contribute to a significant socioeconomic burden.Purpose: To examine the clinical performance and safety of a collagen-alginate dressing in combination with standard wound care in non-healing VLUs.Methods: In an observational, explorative, single-center study, VLUs of 60 patients were covered with a collagen-alginate dressing. Wounds were assessed during 5 visits over a 4-week period. At the final visit, health care professionals gave an overall assessment of the dressing. Outcome parameters were wound area reduction, wound pain, wound-related quality of life (QoL), and incidence of adverse events.Results: The mean wound area decreased (17.8 ± 11.2 cm² versus 11.4 ± 9.0 cm²; P < .0001), and 4 patients achieved complete closure. Wound pain decreased after 2 weeks, and intake of analgesics reduced. Patients' wound-related QoL improved and a correlation between the well-being sub-score and wound area reduction was found. All health care professionals rated the collagen-alginate dressing as 'very good' or 'good.'Conclusion: The collagen-alginate dressing is safe and effective in promoting healing and addressing the pain of VLUs. It also improves patients' QoL, possibly by reducing wound area, pain, and exudate.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 4","pages":""},"PeriodicalIF":1.0000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wound management & prevention","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.25270/wmp.23113","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Venous leg ulcers (VLUs) are associated with various physical and social adverse effects for patients but also contribute to a significant socioeconomic burden.

Purpose: To examine the clinical performance and safety of a collagen-alginate dressing in combination with standard wound care in non-healing VLUs.

Methods: In an observational, explorative, single-center study, VLUs of 60 patients were covered with a collagen-alginate dressing. Wounds were assessed during 5 visits over a 4-week period. At the final visit, health care professionals gave an overall assessment of the dressing. Outcome parameters were wound area reduction, wound pain, wound-related quality of life (QoL), and incidence of adverse events.

Results: The mean wound area decreased (17.8 ± 11.2 cm² versus 11.4 ± 9.0 cm²; P < .0001), and 4 patients achieved complete closure. Wound pain decreased after 2 weeks, and intake of analgesics reduced. Patients' wound-related QoL improved and a correlation between the well-being sub-score and wound area reduction was found. All health care professionals rated the collagen-alginate dressing as 'very good' or 'good.'

Conclusion: The collagen-alginate dressing is safe and effective in promoting healing and addressing the pain of VLUs. It also improves patients' QoL, possibly by reducing wound area, pain, and exudate.

查看原文本刊更多论文

天然海藻酸胶原敷料治疗下肢静脉溃疡的观察性研究及其对伤口相关生活质量的影响。

背景：下肢静脉性溃疡（VLUs）与患者的各种身体和社会不良反应有关，但也造成了重大的社会经济负担。目的：探讨海藻酸胶原敷料联合标准创面护理治疗未愈合vlu的临床疗效和安全性。方法：在一项观察性、探索性、单中心研究中，对60例患者的vlu进行海藻酸胶原敷料覆盖。在4周的时间内进行5次访问评估伤口。在最后一次访问中，卫生保健专业人员对敷料进行了全面评估。结果参数为伤口面积减少、伤口疼痛、伤口相关生活质量（QoL）和不良事件发生率。结果：平均创面面积减少(17.8±11.2 cm²比11.4±9.0 cm²；P < 0.0001)， 4例患者完全闭合。2周后伤口疼痛减轻，镇痛药的摄入量减少。患者的伤口相关生活质量得到改善，幸福感评分与伤口面积减少之间存在相关性。所有的卫生保健专业人员都将胶原藻酸盐敷料评为“非常好”或“好”。结论：海藻酸胶原蛋白敷料具有安全、有效的促愈合作用。它还可能通过减少伤口面积、疼痛和渗出来改善患者的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊